Amine　and　phenol　derivatives　of　high　boiling　point　solvent　(HBS)　lignin　were　prepared　by　Mannich　reaction　and　phenolic　reaction,　respectively.　The　bromelain　adsorption　with　HBS　lignin　and　its　derivatives　was　investigated.　The　results　showed　that　the　adsorption　abilities　of　amine　and　phenol　derivatives　of　HBS　lignin　were　improved　greatly.　The　order　of　their　adsorption　capacities　to　bromelain　was　as　follows:　HBS　lignin　amine　＞　HBS　lignin　phenol　＞　HBS　lignin.　The　activity　of　the　bromelain　was　kept　at　a　high　level　after　the　adsorption.　The　HBS　lignin　and　its　derivatives　could　be　used　as　new　concentrated　adsorbents　of　bromelain　or　new　carriers　in　bromelain　immobilization.