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< Page ,Total 12568 >
Drosophila models used to simulate human ATP1A1 gene mutations that cause Charcot-Marie-Tooth type 2 disease and refractory seizures SCIE
期刊论文 | 2025 , 20 (1) , 265-276 | NEURAL REGENERATION RESEARCH
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Abstract :

Certain amino acids changes in the human Na+/K+-ATPase pump, ATPase Na+/K+ transporting subunit alpha 1 (ATP1A1), cause Charcot-Marie-Tooth disease type 2 (CMT2) disease and refractory seizures. To develop in vivo models to study the role of Na+/K+-ATPase in these diseases, we modified the Drosophila gene homolog, Atp alpha, to mimic the human ATP1A1 gene mutations that cause CMT2. Mutations located within the helical linker region of human ATP1A1 (I592T, A597T, P600T, and D601F) were simultaneously introduced into endogenous DrosophilaAtp alpha by CRISPR/Cas9-mediated genome editing, generating the Atp alpha(TTTF) model. In addition, the same strategy was used to generate the corresponding single point mutations in flies (Atp alpha(I571T), Atp alpha(A576T), Atp alpha(P579T), and Atp alpha(D580F)). Moreover, a deletion mutation (Atp alpha(mut)) that causes premature termination of translation was generated as a positive control. Of these alleles, we found two that could be maintained as homozygotes (Atp alpha(I571T) and Atp alpha(P579T)). Three alleles (Atp alpha(A576T), Atp alpha(P579) and Atp alpha(D580F)) can form heterozygotes with the Atp alpha(mut) allele. We found that the Atp alpha allele carrying these CMT2-associated mutations showed differential phenotypes in Drosophila. Flies heterozygous for Atp alpha(TTTF) mutations have motor performance defects, a reduced lifespan, seizures, and an abnormal neuronal morphology. These Drosophila models will provide a new platform for studying the function and regulation of the sodium-potassium pump.

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Atp alpha bang-sensitive paralysis Charcot-Marie-Tooth disease type 2 CRISPR/Cas9 homology-directed repair Na+/K+-ATPase point mutation seizures sodium pump

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GB/T 7714 Yuan, Yao , Yu, Lingqi , Zhuang, Xudong et al. Drosophila models used to simulate human ATP1A1 gene mutations that cause Charcot-Marie-Tooth type 2 disease and refractory seizures [J]. | NEURAL REGENERATION RESEARCH , 2025 , 20 (1) : 265-276 .
MLA Yuan, Yao et al. "Drosophila models used to simulate human ATP1A1 gene mutations that cause Charcot-Marie-Tooth type 2 disease and refractory seizures" . | NEURAL REGENERATION RESEARCH 20 . 1 (2025) : 265-276 .
APA Yuan, Yao , Yu, Lingqi , Zhuang, Xudong , Wen, Dongjing , He, Jin , Hong, Jingmei et al. Drosophila models used to simulate human ATP1A1 gene mutations that cause Charcot-Marie-Tooth type 2 disease and refractory seizures . | NEURAL REGENERATION RESEARCH , 2025 , 20 (1) , 265-276 .
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Sodium citrate enhancing electrodeposition of metallic arsenic from toxic trivalent arsenic and the mechanism understanding Scopus
期刊论文 | 2025 , 151 , 79-87 | Journal of Environmental Sciences (China)
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Abstract :

Electrochemical conversion of hypertoxic trivalent arsenic to value-added metallic arsenic can not only contribute to pollution abatement, but also resources reutilization, therefore being widely explored. Electrochemical reduction of trivalent arsenic as a promising way is widely explored. However, the high efficiency conversion is retarded by the sluggish reduction kinetics of AsO33− and fierce evolution of side products of both H2 and toxic AsH3. Herein, by using the sodium citrate as the additive, the current efficiency for metal arsenic production is increased greatly from 60% to 91%, with the accompanied evolution of hypertoxic AsH3 being restrained from 0.15 Nm3/tAs to 0.022 Nm3/tAs, promising a high-efficiency and green process. The electrochemical tests and electrode surface characterizations as well as DFT calculations indicate that the added sodium citrate promotes both the diffusion of reactive AsO33− towards the cathode and its subsequent adsorption on the Ti cathode, contributing to smoother reduction for generating metal arsenic, with the evolution of toxic AsH3 being hindered at the same time. The results can provide new insights for the high-efficiency and greener conversion of hypertoxic trivalent arsenic to value-added metallic arsenic. © 2024

Keyword :

Electrochemical conversion Metallic arsenic Sodium citrate Toxic arsenic

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GB/T 7714 Zhong, S. , Xu, T. , Chen, H. et al. Sodium citrate enhancing electrodeposition of metallic arsenic from toxic trivalent arsenic and the mechanism understanding [J]. | Journal of Environmental Sciences (China) , 2025 , 151 : 79-87 .
MLA Zhong, S. et al. "Sodium citrate enhancing electrodeposition of metallic arsenic from toxic trivalent arsenic and the mechanism understanding" . | Journal of Environmental Sciences (China) 151 (2025) : 79-87 .
APA Zhong, S. , Xu, T. , Chen, H. , Tang, D. , Tan, W. , Weng, W. et al. Sodium citrate enhancing electrodeposition of metallic arsenic from toxic trivalent arsenic and the mechanism understanding . | Journal of Environmental Sciences (China) , 2025 , 151 , 79-87 .
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Judiciously designed dual cross-linked networks for highly transparency, robustness and flexibility in liquid-repellent coatings Scopus
期刊论文 | 2025 , 206 , 53-61 | Journal of Materials Science and Technology
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Highly transparent, durable, and flexible liquid-repellent coatings are urgently needed in the realm of transparent materials, such as car windows, optical lenses, solar panels, and flexible screen materials. However, it has been difficult to strike a balance between the robustness and flexibility of coatings constructed by a single cross-linked network design. To overcome the conundrum, this innovative approach effectively combines two distinct cross-linked networks with unique functions, thus overcoming the challenge. Through a tightly interwoven structure comprised of added crosslinking sites, the coating achieves improved liquid repellency (WCA>100°, OSA<10°), increased durability (withstands 2,000 cycles of cotton wear), enhanced flexibility (endures 5,000 cycles of bending with a bending radius of 1 mm), and maintains high transparency (over 98 % in the range of 410 nm to 760 nm). Additionally, the coating with remarkable adhesion can be applied to multiple substrates, enabling large-scale preparation and easy cycling coating, thus expanding its potential applications. The architecture of this fluoride-free dual cross-linked network not only advances liquid-repellent surfaces but also provides valuable insights for the development of eco-friendly materials in the future. © 2024

Keyword :

Dual cross-linked network Flexible liquid-like coating Fluoride-free Highly transparent Tight entanglement

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GB/T 7714 Wu, S. , Cheng, Y. , Zheng, W. et al. Judiciously designed dual cross-linked networks for highly transparency, robustness and flexibility in liquid-repellent coatings [J]. | Journal of Materials Science and Technology , 2025 , 206 : 53-61 .
MLA Wu, S. et al. "Judiciously designed dual cross-linked networks for highly transparency, robustness and flexibility in liquid-repellent coatings" . | Journal of Materials Science and Technology 206 (2025) : 53-61 .
APA Wu, S. , Cheng, Y. , Zheng, W. , Deng, Y. , Zhu, T. , Zhang, W. et al. Judiciously designed dual cross-linked networks for highly transparency, robustness and flexibility in liquid-repellent coatings . | Journal of Materials Science and Technology , 2025 , 206 , 53-61 .
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Research on entertainment robots based on artificial intelligence interaction for human posture recognition and sports activity monitoring Scopus
期刊论文 | 2025 , 52 | Entertainment Computing
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Abstract :

With the application of artificial intelligence technology in sports activity monitoring, new technologies such as interactive robots and the Internet of Things are being more widely used, which can provide entertainment and interactive guidance for sports training. This article analyzes the research on human pose recognition and sports activity monitoring of entertainment robots based on artificial intelligence interaction. This paper designs and develops an entertainment robot system that can recognize human posture and monitor physical activities. Users can interact with the robot and get real-time feedback about their posture and activities, thereby improving motor skills and physical fitness. After in-depth analysis of the theory of dynamic Bayesian network, we used EM algorithm to build a dynamic Bayesian network model, carried out detailed research on the random variables represented by the nodes of the dynamic model, and used the Internet of Things human posture recognition technology to extract the features of human behavior according to the characteristics of human behavior. The results show that the attitude recognition accuracy can be improved by adding the dynamic Bayesian network based on the random forest algorithm. The entertainment robot can accurately identify human posture and monitor sports activities, and has good real-time and stability. Through interaction with the robot, users can get personalized suggestions for individual postures and activities, improving the training effect and enjoyment of physical activities. Therefore, through the in-depth research and analysis of the dynamic Bayesian network and the human posture recognition of the Internet of Things, it is found that the sports activity monitoring system proposed in this paper can comprehensively monitor students’ sports activities, so as to achieve the goal of comprehensively improving students’ physical fitness. © 2024 Elsevier B.V.

Keyword :

Activity monitoring Artificial intelligence interaction Entertainment robots Human posture recognition Sports

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GB/T 7714 Xiaochun, C. . Research on entertainment robots based on artificial intelligence interaction for human posture recognition and sports activity monitoring [J]. | Entertainment Computing , 2025 , 52 .
MLA Xiaochun, C. . "Research on entertainment robots based on artificial intelligence interaction for human posture recognition and sports activity monitoring" . | Entertainment Computing 52 (2025) .
APA Xiaochun, C. . Research on entertainment robots based on artificial intelligence interaction for human posture recognition and sports activity monitoring . | Entertainment Computing , 2025 , 52 .
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ZIF-7-NH2 functionalized collagen fibers for effective and selective mercury ion capture Scopus
期刊论文 | 2025 , 353 | Separation and Purification Technology
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Adsorptive removal of mercury ion from wastewater has become a hot topic due to the toxicity and persistence; acquiring adsorbent materials with high-capacity, rapid-kinetic, super-selective while low-cost features are highly demanded. Herein, based on the full functionality of collagen fiber (CF) from the leather waste, we proposed an innovative synthetic approach through exploiting amino-functionalized ZIF-7 (ZIF-7-NH2) as functional groups to facilely in-situ incorporate with CF, affording low-cost but effective adsorbent materials of CF/ZIF-7-NH2 composite maximizing both functions of CF and ZIF-7-NH2 in the Hg(II) capture. Remarkably, it exhibits an ultra-high capacity as high as 909.09 mg g-1, fast kinetics that could remove 99.01 % of 200 mg·L-1 within 20 min, and significant selectivity of SHg/M (KdHg/KdM) as large as 522–1017 over Mg2+, K+, Ca2+, Cd2+, and Mn2+. We understand such an impressive adsorption is contributed by the synergistic action between functional groups including on the CF and ZIF-7-NH2. This study offers an effective method for removing heavy metal ions, achieving efficient removal of Hg(II) ions for pollution control, and promoting the reuse of waste CF to reduce waste accumulation in various aspects. © 2024 Elsevier B.V.

Keyword :

Adsorptive separation Collagen fiber Hg(II) removal High-capacity ZIFs

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GB/T 7714 Ye, X. , Zheng, Z. , Zhu, J. et al. ZIF-7-NH2 functionalized collagen fibers for effective and selective mercury ion capture [J]. | Separation and Purification Technology , 2025 , 353 .
MLA Ye, X. et al. "ZIF-7-NH2 functionalized collagen fibers for effective and selective mercury ion capture" . | Separation and Purification Technology 353 (2025) .
APA Ye, X. , Zheng, Z. , Zhu, J. , Chen, J. , Zhou, J. , Shi, B. . ZIF-7-NH2 functionalized collagen fibers for effective and selective mercury ion capture . | Separation and Purification Technology , 2025 , 353 .
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Tailoring the morphology and charge transfer pathways of ultrathin Cd0.8Zn0.2S nanosheets via ionic liquid-modified Ti3C2 MXenes towards remarkable photocatalytic hydrogen evolution Scopus
期刊论文 | 2025 , 204 , 47-59 | Journal of Materials Science and Technology
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Abstract :

Small-sized CdxZn1–xS solid solution nanomaterial is an important candidate for efficient photocatalytic hydrogen evolution (PHE), but it still suffers from easy agglomeration, severe photo corrosion, and fast photogenerated electron-hole recombination. To tackle these issues, herein, we propose a new strategy to modify CdxZn1–xS nanoreactors by the simultaneous utilization of ionic-liquid)-assisted morphology engineering and MXene-incorporating method. That is, we designed and synthesized a novel hierarchical Cd0.8Zn0.2S/Ti3C2 Schottky junction composite through the in-situ deposition of ultrathin Cd0.8Zn0.2S nanosheets on unique IL-modified Ti3C2 MXenes by a one-pot solvothermal method for efficiently PHE. The unique construction strategy tailors the thickness of ultrathin Cd0.8Zn0.2S nanosheets and prevents them from stacking and agglomeration, and especially, optimizes their charge transfer pathways during the photocatalytic process. Compared with pristine Cd0.8Zn0.2S nanosheets, Cd0.8Zn0.2S/Ti3C2 has abundant photogenerated electrons available on the Ti3C2 surface for proton reduction reaction, owing to the absence of deep-trapped electrons, suppression of electron-hole recombination in Cd0.8Zn0.2S and high-efficiency charge separation at the Cd0.8Zn0.2S/Ti3C2 Schottky junction interface. Moreover, the hydrophilicity, electrical conductivity, visible-light absorption capacity, and surficial hydrogen desorption of Cd0.8Zn0.2S/Ti3C2 heterostructure are significantly improved. As a result, the heterostructure exhibits outstanding photocatalytic stability and super high apparent quantum efficiency, being rendered as one of the best noble-metal-free Cd-Zn-S-based photocatalysts. This work illustrates the mechanisms of morphology control and heterojunction construction in controlling the catalytic behavior of photocatalysts and highlights the great potential of the IL-assisted route in the synthesis of high-performance MXene-based heterostructures for photocatalytic hydrogen evolution. © 2024

Keyword :

Ionic liquid MXene Photocatalytic H2 evolution Photoexcited charge separation Schottky junction Ultrathin Cd0.8Zn0.2S nanosheets

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GB/T 7714 Hu, Q. , Yin, H. , Liu, Y. et al. Tailoring the morphology and charge transfer pathways of ultrathin Cd0.8Zn0.2S nanosheets via ionic liquid-modified Ti3C2 MXenes towards remarkable photocatalytic hydrogen evolution [J]. | Journal of Materials Science and Technology , 2025 , 204 : 47-59 .
MLA Hu, Q. et al. "Tailoring the morphology and charge transfer pathways of ultrathin Cd0.8Zn0.2S nanosheets via ionic liquid-modified Ti3C2 MXenes towards remarkable photocatalytic hydrogen evolution" . | Journal of Materials Science and Technology 204 (2025) : 47-59 .
APA Hu, Q. , Yin, H. , Liu, Y. , Ablez, A. , Wang, Z. , Zhan, Y. et al. Tailoring the morphology and charge transfer pathways of ultrathin Cd0.8Zn0.2S nanosheets via ionic liquid-modified Ti3C2 MXenes towards remarkable photocatalytic hydrogen evolution . | Journal of Materials Science and Technology , 2025 , 204 , 47-59 .
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Occurrence and potential risks of organophosphate esters in agricultural soils: A case study of Fuzhou City, Southeast China Scopus
期刊论文 | 2025 , 150 , 571-581 | Journal of Environmental Sciences (China)
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Abstract :

Fifty agricultural soil samples collected from Fuzhou, southeast China, were first investigated for the occurrence, distribution, and potential risks of twelve organophosphate esters (OPEs). The total concentration of OPEs (ΣOPEs) in soil ranged from 1.33 to 96.5 ng/g dry weight (dw), with an average value of 17.1 ng/g dw. Especially, halogenated-OPEs were the predominant group with a mean level of 9.75 ng/g dw, and tris(1-chloro-2-propyl) phosphate (TCIPP) was the most abundant OPEs, accounting for 51.1% of ΣOPEs. The concentrations of TCIPP and ∑OPEs were found to be significantly higher (P < 0.05) in soils of urban areas than those in suburban areas. In addition, the use of agricultural plastic films and total organic carbon had a positive effect on the occurrence of OPE in this study. The positive matrix factorization model suggested complex sources of OPEs in agricultural soils from Fuzhou. The ecological risk assessment demonstrated that tricresyl phosphate presented a medium risk to land-based organisms (0.1 ≤ risk quotient < 1.0). Nevertheless, the carcinogenic and non-carcinogenic risks for human exposure to OPEs through soil ingestion and dermal absorption were negligible. These findings would facilitate further investigations into the pollution management and risk control of OPEs. © 2024

Keyword :

Agricultural soils Organophosphate esters (OPEs) Risk assessment Source identification Spatial distribution

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GB/T 7714 Wang, T. , Zhang, H. , Huang, C. et al. Occurrence and potential risks of organophosphate esters in agricultural soils: A case study of Fuzhou City, Southeast China [J]. | Journal of Environmental Sciences (China) , 2025 , 150 : 571-581 .
MLA Wang, T. et al. "Occurrence and potential risks of organophosphate esters in agricultural soils: A case study of Fuzhou City, Southeast China" . | Journal of Environmental Sciences (China) 150 (2025) : 571-581 .
APA Wang, T. , Zhang, H. , Huang, C. , Ben, Y. , Zhou, H. , Guo, H. et al. Occurrence and potential risks of organophosphate esters in agricultural soils: A case study of Fuzhou City, Southeast China . | Journal of Environmental Sciences (China) , 2025 , 150 , 571-581 .
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A microporous framework with aromatic pores for one-step purification of C2F6 from CF3CH2F/CF3CHF2/C2F6 mixture Scopus
期刊论文 | 2025 , 353 | Separation and Purification Technology
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Separating C2F6 from CF3CH2F/CF3CHF2/C2F6 is of great importance since electronic grade C2F6 is an important plasma etching gas that can be used for surface cleaning of electronic devices, as well as microelectronics, fiber optic cables and solar cells. Herein, a four-fold intermingled MOF material Ni(pba)2 was constructed, which has a high selectivity of CF3CH2F/C2F6 (38.8) and CF3CHF2/C2F6 (19.8). Breakthrough experiments show that high-purity C2F6 can not only be obtained from the binary CF3CHF2/C2F6 (5/95, v/v) and CF3CH2F/C2F6 (5/95, v/v) mixtures but also can be directly collected from ternary CF3CH2F/CF3CHF2/C2F6 (5/5/90, v/v/v) mixture with a high productivity of 7.1 mol/kg. Additionally, it is found that Ni(pba)2 can maintain good separation performance under different conditions. Finally, the theoretical calculation results show that the interactions between C2F6 and the aromatic pores are significantly lower than those of CF3CHF2 and CF3CH2F, which leads to good C2F6 separation performance. © 2024 Elsevier B.V.

Keyword :

Electronic gases Hexafluoroethane Metal-Organic Framework Separation

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GB/T 7714 Zhu, Y. , Zhou, Y. , Ji, Z. et al. A microporous framework with aromatic pores for one-step purification of C2F6 from CF3CH2F/CF3CHF2/C2F6 mixture [J]. | Separation and Purification Technology , 2025 , 353 .
MLA Zhu, Y. et al. "A microporous framework with aromatic pores for one-step purification of C2F6 from CF3CH2F/CF3CHF2/C2F6 mixture" . | Separation and Purification Technology 353 (2025) .
APA Zhu, Y. , Zhou, Y. , Ji, Z. , Zhang, W. , Wu, M. . A microporous framework with aromatic pores for one-step purification of C2F6 from CF3CH2F/CF3CHF2/C2F6 mixture . | Separation and Purification Technology , 2025 , 353 .
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Eco-friendly biomass aerogels from moxibustion waste for sustainable remediation of organic contaminants Scopus
期刊论文 | 2025 , 353 | Separation and Purification Technology
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Powder adsorbents present limited recyclability when used for wastewater treatment. Bulk materials prepared via eco-friendly approaches typically exhibit excellent reproducibility over powders in terms of removing pollutants from aquatic environments. Here, biomass-based aerogels were synthesized via ball milling a mixture of modified moxa ash (a type of moxibustion waste), carbon nanotubes and ammonia, combined with agarose as biomolecule. The obtained aerogels display low density, high porosity, remarkable mechanical properties, and exceptional repeatability and stability for removing organic pollutants. By employing a two-dimensional (2D) aerogel membrane, pollutants such as 10 mg/L mitoxantrone (MTX), 5 mg/L methylene blue, 5 mg/L malachite green, or 5 mg/L rhodamine B could be dynamically adsorbed and swiftly filtered out, achieving nearly 100 % of the removal rate. For three-dimensional (3D) aerogels, efficient removals of MTX (98.4 % at 135 min) and cationic dyes under various conditions were observed, in which the adsorption capacity reached 28.23 mg/g for low concentration of MTX at 120 min. After four cycles, the aerogel still retained 93 % of its original capacity and the removal rate was still 92.4 %. The adsorption process obeys second-order kinetics and adheres to the Freundlich and Temkin isotherm models. Furthermore, the primary mechanism by which the aerogels adsorb MTX includes pore filling, electrostatic interactions, π-π conjugation and hydrogen bonding. The adsorption mechanism was better explained by the results of density functional theory. Biomass-based 2D/3D aerogels are promising, low-cost, eco-friendly and highly efficient absorbents for mitigating wastewater contamination. © 2024 Elsevier B.V.

Keyword :

Adsorption mechanism Aerogel Mitoxantrone Moxa ash Pollutant removal

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GB/T 7714 Wu, Y. , Cai, W. , Wen, J. et al. Eco-friendly biomass aerogels from moxibustion waste for sustainable remediation of organic contaminants [J]. | Separation and Purification Technology , 2025 , 353 .
MLA Wu, Y. et al. "Eco-friendly biomass aerogels from moxibustion waste for sustainable remediation of organic contaminants" . | Separation and Purification Technology 353 (2025) .
APA Wu, Y. , Cai, W. , Wen, J. , Zhong, S. , Jiang, X. , Lin, C. et al. Eco-friendly biomass aerogels from moxibustion waste for sustainable remediation of organic contaminants . | Separation and Purification Technology , 2025 , 353 .
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Engineering biodegradable bacterial cellulose/polylactic acid multi-scale fibrous membrane via co-electrospinning-electrospray strategy for efficient, wet-stable, durable PM0.3 filtration Scopus
期刊论文 | 2025 , 352 | Separation and Purification Technology
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Abstract :

Airborne pollution, derived from tiny particulate matter (PM) and the pandemic virus, strongly stimulates the demand for personal protective materials but also causes serious environmental issues due to the mass discarding of disposable nondegradable face masks. Despite a few reports of bio-based filters, however, it remains a challenge to develop biodegradable respirators with efficient, wet-stable PM0.3 filtration and low pressure drop. Herein, the degradable multi-scale fibrous filter composed of polylactic acid (PLA) micro-/submicron-fibers and bacterial cellulose (BC) nanofibers was rationally designed to balance the filtration efficiency and resistance. The 2D BC nano-mesh with the small pores was self-assembled by the electro-spraying technique and the PLA submicron-fibrous networks with medium pores were prepared by the electrospinning technology. The multilayer micro-/submicron-/nano-fiber construction endowed the membrane with a low pore size of 1.27 μm and also extended the particle flow path, which contributed to the efficient and durable PM0.3 interception. As a result, the prepared filter showed over 99.89% PM0.3 filtration efficiency but a low pressure drop of 104 Pa. More significantly, it still presented over 99.68% PM0.3 removal after long-term filtration under 90% RH. This work may provide meaningful guidance for the development of biodegradable high-protective air filters. © 2024 Elsevier B.V.

Keyword :

Biodegradability Electrospinning Electrospray Multi-scale fibrous membrane PM0.3 filtration

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GB/T 7714 Yang, Y. , Zhong, M. , Wang, W. et al. Engineering biodegradable bacterial cellulose/polylactic acid multi-scale fibrous membrane via co-electrospinning-electrospray strategy for efficient, wet-stable, durable PM0.3 filtration [J]. | Separation and Purification Technology , 2025 , 352 .
MLA Yang, Y. et al. "Engineering biodegradable bacterial cellulose/polylactic acid multi-scale fibrous membrane via co-electrospinning-electrospray strategy for efficient, wet-stable, durable PM0.3 filtration" . | Separation and Purification Technology 352 (2025) .
APA Yang, Y. , Zhong, M. , Wang, W. , Lu, N. , Gou, Y. , Cai, W. et al. Engineering biodegradable bacterial cellulose/polylactic acid multi-scale fibrous membrane via co-electrospinning-electrospray strategy for efficient, wet-stable, durable PM0.3 filtration . | Separation and Purification Technology , 2025 , 352 .
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