Few　works　focus　on　the　process　intensification　of　extractive　distillation　(ED)　for　the　separation　of　ternary　mixture　with　two　binary　azeotropes　due　to　its　complexity.　In　this　work,　double-effect　heat　integration　(DEHI),　intermediate　reboiler　(IR)　and　vapor　recompression　(VRC)　heat　pump　ED　intensification　processes　for　separating　tetrahydrofuran-methanol-water　mixture　are　proposed　and　optimized　via　multi-objective　genetic　algorithm　to　reduce　the　CO2　emissions　and　the　total　annual　cost.　Furthermore,　each　of　the　ED　intensification　process　is　combined　with　the　full　use　of　the　sensible　heat　in　entrainer　recycling　stream.　The　results　showed　that　all　the　proposed　ED　intensification　processes　are　energy-saving　than　the　conventional　one.　The　combined　DEHI　process　is　the　most　economic　since　its　TAC　(3　years　payback　period)　is　reduced　by　25.1%　while　the　combined　VRC　is　the　most　eco-friendly　as　its　CO2　emissions　are　saved　by　30.4%　compared　with　the　conventional　ED　process.