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Abstract:
Conventional photosensitizer-based photodynamic therapy is triggered by UV-light irradiation and depends on oxygen. However, it is hard to be applied to the deep and hypoxic tumor. To address this issue, we reported a new kind of g-C3N4 nanosheet decorated with gold nanoparticles (AuNPs), which could generate a high amount of reactive oxygen species (ROS) under a 670 nm laser irradiation in an oxygen-free environment. This synthesized semiconductor metal heterojunction served as a superior photodynamic agent, showing prominent cancer cell-killing and tumor growth-suppressing effects in the presence of a 670 nm light and g-C3N4-AuNP composites, and its excellent ROS generation property was also validated by further bactericidal experiment.
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ACS APPLIED MATERIALS & INTERFACES
ISSN: 1944-8244
Year: 2019
Issue: 11
Volume: 11
Page: 10589-10596
8 . 7 5 8
JCR@2019
8 . 5 0 0
JCR@2023
ESI Discipline: MATERIALS SCIENCE;
ESI HC Threshold:236
JCR Journal Grade:1
CAS Journal Grade:2
Cited Count:
WoS CC Cited Count: 79
SCOPUS Cited Count: 82
ESI Highly Cited Papers on the List: 0 Unfold All
WanFang Cited Count:
Chinese Cited Count:
30 Days PV: 0
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