In　this　paper,　we　propose　a　scheme　for　realizing　nonadiabatic　holonomic　computation　assisted　by　two　atoms　and　the　shortcuts　to　adiabaticity　(STA).　The　blockade　effect　induced　by　strong　Rydberg-mediated　interaction　between　two　Rydberg　atoms　provides　us　the　possibility　to　simplify　the　dynamics　of　the　system,　and　the　STA　helps　us　design　pulses　for　implementing　the　holonomic　computation　with　high　fidelity.　Numerical　simulations　show　the　scheme　is　noise　immune　and　decoherence　resistant.　Therefore,　the　current　scheme　may　provide　some　useful　perspectives　for　realizing　nonadiabatic　holonomic　computation.