The　assessment　and　control　of　nitrogen　and　phosphorus　runoff　losses　from　paddy　fields　are　important　to　protect　water　quality　in　the　Taihu　Lake　Region　of　China.　A　three-year　field　study　was　conducted　to　investigate　the　effect　of　different　water　and　nitrogen　management　practices　on　nitrogen　and　phosphorus　runoff　losses　from　paddy　fields.　Results　showed　that　compared　with　drainage　water　from　traditional　irrigation　paddy　fields,　drainage　water　from　controlled　irrigation　(CI)　paddy　fields　had　a　higher　drainage　volume　when　continuous　rain　occurred　and　lower　drainage　times　and　volume　when　rainfall　was　low　and　momentary.　The　drainage　water　from　the　first　drainage　event　had　the　maximum　nitrogen　and　phosphorus　concentrations,　which　were　caused　by　the　basal　application　of　fertilizer　and　low　uptake　activity　of　rice.　CI　and　optimized　nitrogen　fertilizer　management　both　reduced　total　nitrogen　(TN)　and　ammonia　nitrogen　concentrations　in　drainage　water　from　paddy　fields.　Compared　with　the　traditional　water　and　nitrogen　management　practices,　the　joint　CI　and　Site-specific　nitrogen　management,　controlled　release　nitrogen　fertilizer　management　can　further　reduced　TN　concentration　in　drainage　water　by　30.70%-72.31%　and　53.02%-78.75%,　respectively.　Moreover,　the　joint　regulation　of　water-saving　irrigation　and　optimized　nitrogen　fertilizer　management　effectively　reduced　the　runoff　loss　of　nitrogen　by　49.32%-78.27%.　Water　and　nitrogen　management　practices　had　little　influence　on　the　runoff　loss　of　total　phosphorus　from　paddy　fields.