Nanocrystalline　MTiO3　(M　=　Sr,　Pb,　Co)　were　prepared　by　a　general　self-propagating　combustion　method.　The　samples　were　characterized　by　X-ray　diffraction　(XRD)　analysis,　scanning　electron　microscopy　(SEM),　transmission　electron　microscopy　(TEM),　N-2　adsorption　and　UV-vis　diffuse　reflectance　spectra　(DRS).　The　photocatalytic　activity　of　MTiO3　(M　=　Sr,　Pb,　Co)　was　evaluated　by　the　photocatalytic　degradation　of　methyl　orange　(MO).　MTiO3　(M　=　Sr,　Pb,　Co)　having　the　same　core　element　showed　distinctly　different　photocatalytic　activity　due　to　the　different　coordinating　atoms.　Factors　affecting　the　photocatalytic　activity　of　MTiO3　(M　=　Sr,　Pb,　Co)　were　discussed.　It　was　suggested　that　the　structures　of　TiO6　octahedra　and　the　electronic　property　were　the　predominant　factors　of　the　photocatalytic　behavior　for　MTiO3　(M　=　Sr,　Pb,　Co).