A　capillary　electrophoresis　system　coupled　with　wall-jet　amperometric　detection　was　used　to　determine　five　flavonoids　(kaempferol,　rutin,　hyperoside,　quercitrin,　quercetin)　in　Herba　Leonuri.　Several　important　effect　factors,　such　as　the　pH　and　concentration　of　running　buffer,　separation　voltage,　injection　time,　and　detection　potential,　were　investigated　to　acquire　the　optimum　conditions.　With　50　mmoL/L　Na2B4O7-100　mmoL/L　NaH2PO4　buffer　(pH=7.50)　as　the　running　buffer,　the　five　flavonoids　were　baseline　separated　within　15　min　in　a　60　cm　length　capillary　at　a　separation　voltage　of　15　kV.　The　relationship　between　peak　currents　and　analyte　concentrations　was　linear　over　about　2　orders　of　magnitude,　with　detection　limits　(S/N　=　3)　ranging　from　0.03　to　0.08　mu　g/mL　for　all　analytes.　The　use　of　this　method　for　the　quantitation　of　the　above　flavonoids　present　in　the　real　sample　of　Herba　Leonuri　was　reported.