The　title　compound　[(VO)(H2O)(2)(SeO3)](2)[(H(2)pipe)SO4]　was　synthesized　under　hydrothermal　condition　with　VOSO4,　piperazidine　(pipe),　and　SeO2,　and　its　crystal　structure　was　established　using　single-crystal　X-ray　diffraction　method.　The　title　compound　was　characterized　with　IRsquareFluorescence.　The　crystal　data:　P-1　(No.　2),　a　=　8.633(　2)　Angstrom,　b　=　9.223(　2)　Angstrom,　c　=　12.508(3)　Angstrom,　alpha　=　109.28(3)degrees,　beta　=　90.42(3)degrees,　gamma　=　107.79(3)degrees,　Mr　=　644.08,　V　=　888.5(3)　Angstrom(3),　Z　=　2,　Dc　=　2.407　g　cm(-3),　mu　=　5.350　mm(-1),　F(000)　=　632.　The　structure　of　the　title　compound　consists　of　an　infinite　neutral　ladder　chain,　which　is　built　up　from　VO6　octahedral　and　SeO3　pyramidal　units　sharing　vertices,　and　organic　salt.　The　biprotonized　pipe　(piperazidine)　and　SO42-　interact　with　one　another　and　the　inorganic　chain　through　strong　hydrogen　bonds　N-H...O　or　O-H...O　to　give　a　3D　structure.　Hydrogen　bonds　play　a　role　of　stabilization　structure.