This　paper　seeks　to　address　the　question　of　how　the　type　of　agglomeration　externalities　impacts　on　the　type　of　entrepreneurship　at　the　regional　level.　Using　China＇s　provincial　panel　data　from　2003　to　2015,　we　employ　the　Generalised　Moment　Method　to　test　the　role　of　regional　specialisation　and　geographic　concentration　in　necessity-driven　and/or　opportunity-driven　entrepreneurship.　In　general,　the　empirical　results　show　that　entrepreneurial　activities　motivated　by　opportunity,　rather　than　by　necessity,　tend　to　be　higher　in　a　more　specialised　or　more　concentrated　area　in　the　context　of　creative　industries.　The　results　are　basically　consistent　and　robust　by　regressions　within　different　groups　of　creative　sectors.　The　paper　is　helpful　in　examining　the　channels　by　which　entrepreneurial　activities　can　be　stimulated　by　industries　clustering　strategy.