The　polarization　field　with　the　function　in　carrier　separation　has　aroused　substantial　interest.　For　heterojunction　complexes,　however,　the　static　polarization　field　will　be　inevitably　shielded　by　a　large　number　of　carriers.　Herein,　a　novel　hybrid　consisted　of　single-domain　PbTiO3　coated　by　CdS　particles　was　selected　as　a　model　material　to　prove　that　the　alternating　piezoelectric　field　induced　by　periodic　stress　can　destroy　shielding　effect.　After　the　introduction　of　alternating　piezoelectric　potential　by　using　ultrasonication,　PbTiO3/CdS-10　%　exhibited　a　much　higher　H2　production　rate　by　piezo-photocatalysis　(849.0　μmol　h−1　g−1)　than　by　individual　piezocatalysis　(400.6　μmol　h−1　g−1)　or　photocatalysis　(98.9　μmol　h−1　g−1).　Furthermore,　the　finite　element　simulation　shows　that　PbTiO3/CdS　heterostructure　has　a　superior　piezoelectric　potential　difference　compare　to　pure　PbTiO3　or　pure　CdS.　Based　on　data　analysis,　the　mechanism　about　the　piezo-photo　coupling　effect　was　proposed,　which　will　provide　a　reference　for　the　design　and　development　of　high-efficiency　piezo-photocatalyst.　©　2020　Elsevier　B.V.