The　development　of　efficient　catalyst　for　photoredox-catalyzed　selective　organic　synthesis　has　consitently　been　an　attractive　objective　in　recent　years.　Regarding　semiconductor-based　photocatalysts,　cadmium　sulfide　(CdS)　materials　have　received　extensive　consideration　for　various　photoredox　reactions　because　of　their　suitable　band　gap　(about　2.4　eV)　for　visible　light　response　and　well-matched　band　edge　stations.　In　this　paper,　we　begin　with　a　concise　discussion　of　the　basic　physical　properties　of　CdS　materials,　including　electronic　band　structures,　optical　properties,　crystallographic　structures,　and　phase　transition.　Then,　the　fundamental　principles　of　photocatalytic　organic　transformations　over　CdS　and　the　effect　of　different　active　species　on　the　selective　photoredox　process　are　concisely　summarized.　In　particular,　we　will　highlight　the　photocatalytic　selective　organic　synthesis　application　over　various　CdS-based　photocatalysts,　including　selective　reductions,　oxidations,　and　valorization　of　lignin.　Finally,　the　future　perspectives　and　challenges　in　the　development　of　efficient　CdS-based　photocatalytic　system　toward　selective　organic　synthesis　are　discussed.　It　is　anticipated　that　this　timely　overview　of　recent　advances　in　selective　organic　synthesis　over　CdS-based　materials　would　inspire　the　rational　design　of　CdS　or　other　semiconductor-based　catalysts　with　ameliorated　performances　toward　a　variety　of　artificial　photoredox-catalyzed　selective　organic　transformations　to　value-added　feedstocks　and　beyond.　Copyright　©　2020　American　Chemical　Society.