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author:

Wu, Wei (Wu, Wei.) [1] | Chen, Qiaoling (Chen, Qiaoling.) [2] | Tian, Yishi (Tian, Yishi.) [3] | Xu, Yihui (Xu, Yihui.) [4] | Huang, Yangjie (Huang, Yangjie.) [5] | You, Yi (You, Yi.) [6] | Weng, Zhiqiang (Weng, Zhiqiang.) [7]

Indexed by:

EI

Abstract:

We describe a general method for the synthesis of 5-(trifluoromethyl)isoxazoles by denitrogenative cyclization of vinyl azides with trifluoroacetic anhydride in the presence of NEt3. The scope of this protocol was further extended to the synthesis of perfluoroalkylated isoxazoles. This reaction allows facile synthesis of structurally diverse 5-(perfluoroalkyl)isoxazole derivatives with various vinyl azides. © 2020 the Partner Organisations.

Keyword:

Cyclization

Community:

  • [ 1 ] [Wu, Wei]State Key Laboratory of Photocatalysis on Energy and Environment, Key Laboratory of Molecule Synthesis and Function Discovery, College of Chemistry, Fuzhou University, Fuzhou; 350108, China
  • [ 2 ] [Chen, Qiaoling]State Key Laboratory of Photocatalysis on Energy and Environment, Key Laboratory of Molecule Synthesis and Function Discovery, College of Chemistry, Fuzhou University, Fuzhou; 350108, China
  • [ 3 ] [Tian, Yishi]State Key Laboratory of Photocatalysis on Energy and Environment, Key Laboratory of Molecule Synthesis and Function Discovery, College of Chemistry, Fuzhou University, Fuzhou; 350108, China
  • [ 4 ] [Xu, Yihui]State Key Laboratory of Photocatalysis on Energy and Environment, Key Laboratory of Molecule Synthesis and Function Discovery, College of Chemistry, Fuzhou University, Fuzhou; 350108, China
  • [ 5 ] [Huang, Yangjie]State Key Laboratory of Photocatalysis on Energy and Environment, Key Laboratory of Molecule Synthesis and Function Discovery, College of Chemistry, Fuzhou University, Fuzhou; 350108, China
  • [ 6 ] [You, Yi]State Key Laboratory of Photocatalysis on Energy and Environment, Key Laboratory of Molecule Synthesis and Function Discovery, College of Chemistry, Fuzhou University, Fuzhou; 350108, China
  • [ 7 ] [Weng, Zhiqiang]State Key Laboratory of Photocatalysis on Energy and Environment, Key Laboratory of Molecule Synthesis and Function Discovery, College of Chemistry, Fuzhou University, Fuzhou; 350108, China

Reprint 's Address:

  • [huang, yangjie]state key laboratory of photocatalysis on energy and environment, key laboratory of molecule synthesis and function discovery, college of chemistry, fuzhou university, fuzhou; 350108, china

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Source :

Organic Chemistry Frontiers

ISSN: 2052-4110

Year: 2020

Issue: 14

Volume: 7

Page: 1878-1883

5 . 2 8 1

JCR@2020

4 . 6 0 0

JCR@2023

ESI HC Threshold:160

JCR Journal Grade:1

CAS Journal Grade:1

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 0

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