Mn-Co　mixed　metal　oxide　is　considered　as　efficient　catalyst　for　the　total　oxidation　of　volatile　organic　compounds.　In　this　study,　nanocube-like　metal-organic　frameworks　(Mn3[Co(CN)6]2·nH2O)　are　adopted　as　the　precursor　to　generate　Mn-Co　oxides　with　different　Mn/Co　molar　ratios,　which　affect　little　on　phase　structure　and　textural　properties.　The　obtained　MOF-Mn1Co1　with　uniform　metal　dispersion　is　rich　in　high　valence　of　surface　Mn4+　and　Co3+　species,　leading　to　high　low-temperature　catalytic　activity　of　total　toluene　oxidation.　The　results　of　toluene-TPD　followed　by　TPO　and　toluene-TPSR　match　well　with　the　catalytic　performances　of　MOF-Mn1Co1,　MOF-Mn1Co2,　and　MOF-Mn2Co1,　and　in　situ　FITR　proves　that　the　benzoate　route　exists　over　MOF-Mn1Co1.　It　is　found　that　a　moderate　ratio　of　Mn/Co　(1:1)　favors　good　low-temperature　reducibility　and　high　Oads/Olatt,　resulting　in　superior　oxidation　performance.　However,　the　stability　in　the　existence　of　water　for　MOF-Mn1Co1　is　not　satisfied,　which　should　be　overcome　in　the　future.　©　2018　Elsevier　B.V.