To　provide　economic　decision　support　for　structural　protection　against　blasting　terror　attacks,　and　to　achieve　the　optimal　balance　between　protection　performance　and　cost,　an　economic　decision　model　for　blast-resistant　protection　measures　of　structures　was　established　in　terms　of　the　relationship　between　cost　of　land　and　blast　protection　measures　and　the　standoff　distance.　Based　on　practical　engineering　data　of　protection　costs　for　anti-blasting,　key　parameters　of　the　prediction　model　were　determined　by　the　trust-region　optimization　algorithm.　The　effectiveness　of　the　established　model　was　verified　with　novel　project　data.　The　results　show　that　the　prediction　model　can　be　used　in　the　economic　analysis　for　the　blast　resistant　protection　measures　in　a　simple　and　effective　manner,　which　provides　evidences　for　blast　security　risk　assessment　and　management　decision.　©　2018,　Engineering　Mechanics　Press.　All　right　reserved.