Aiming　at　the　heterogeneous　multi-attribute　decision　making,　a　variable　weight　decision　making　method　was　proposed　based　on　regret　theory.　The　scheme　relative　closeness　and　variable　weight　vector　were　obtained.　The　regret　aversion　of　decision　makers　were　considered,　the　initial　weight　was　chosen　as　the　reference　point,　and　the　variable　weight　vector　was　transformed　into　the　decision　matrix　of　regret　values　and　rejoice　values　relative　to　the　reference　point.　Furthermore,　by　considering　the　decision　maker＇s　different　risk　attitudes　toward　gains　and　losses,　the　comprehensive　regret-rejoice　values　of　each　alternative　was　calculated　based　on　regret　theory.　A　ranking　of　alternatives　was　determined　by　the　comprehensive　regret-rejoice　values.　The　effectiveness　and　rationality　of　the　proposed　approach　were　illustrated　with　an　actual　example.　©　2017,　Editorial　Department　of　CIMS.　All　right　reserved.