Based　on　real　situations　of　supply　chain　network　among　enterprise　alliances,　this　paper　takes　certain　factors　in　every　round　of　supply　chain　into　consideration　to　establish　robust　model　of　supply　chain　network　design.　Before　that,　the　strategy　“decomposition-　coordination”　is　adopted　to　get　solutions　optimizing　supply　chain　system,　putting　focus　on　the　analysis　of　supplier　selection　cost　and　decision-making　cost　of　supply　chain　facilities,　which　is　integrated　and　coordinated　through　activity-based　costing.　After　the　model　establishment,　examples　are　used　to　illustrate　practicability　and　effectiveness　of　the　model　and　algorithm.　©　2016　SERSC.