A　novel　energy　saving　procedure　for　the　coproduction　of　ethyl　acetate　and　n-butyl　acetate　by　reactive　distillation　is　simulated　by　Aspen　Plus　in　this　paper.　Its　feasibility　is　theoretically　analyzed　on　the　basis　of　the　physical　properties　of　ethyl　acetate/n-butyl　acetate　system.　The　new　procedure　not　only　significantly　reduces　energy　consumption,　but　also　eliminates　the　acetic　acid　purification　column,　as　compared　with　the　individual　processes.　The　outputs　of　ethyl　acetate　and　n-butyl　acetate　can　be　adjusted　flexibly　by　changing　the　feed　molar　ratio　of　ethanol　to　n-butanol　in　a　certain　range.　When　the　feed　molar　ratio　is　less　than　1.0,　the　purity　of　the　products　is　the　same　as　that　for　those　obtained　from　the　individual　procedures.　Also,　energy-saving　increases　as　the　feed　molar　ratio　of　ethanol　to　n-butanol　decreases.　When　the　feed　molar　ratio　of　ethanol　to　n-butanol　is　0.5,　20.40%　energy-saving　is　achieved,　as　compared　with　the　individual　procedures.　At　last,　the　total　annual　cost　(TAC)　of　the　individual　and　coproduction　procedure　is　calculated,　and　the　TAC　of　the　coproduction　is　3-795-912　USD/Y　(U.S.　dollars　per　year)　less　than　the　individuals　5-190-921　USD/Y,　when　10-000　t　EtAc　and　26-363　t　n-BuAc　are　produced.　©　2012　American　Chemical　Society.