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author:

Liu, G. (Liu, G..) [1] | Hong, R.Y. (Hong, R.Y..) [2] | Guo, L. (Guo, L..) [3] | Liu, G.H. (Liu, G.H..) [4] | Feng, B. (Feng, B..) [5] | Li, Y.G. (Li, Y.G..) [6]

Indexed by:

EI

Abstract:

The magnetic fluid (MF) for hyperthermia should be superparamagnetic, non-toxic and biocompatible. The compatibility between blood and dextran-stabilized Fe3O4 MF was first investigated; then the influences of the MF concentration and the magnetic field intensity on the heating ability was studied; at last the effects of temperature, shear rate and applied magnetic field on the viscosity of blood and MF/blood mixtures was measured. The results revealed that the viscosity and coagulation time of blood are almost unaffected by small addition of dextran-stabilized Fe3O4 MF, showing good compatibility with blood. The Fe3O4 MF under alternating magnetic field can generate enough energy to heat tumor tissue for hyperthermia therapy. © 2011 Elsevier B.V.

Keyword:

Biocompatibility Blood Dextran Hyperthermia therapy Iron oxides Magnetic field effects Magnetic fluids Magnetite Shear flow Viscosity

Community:

  • [ 1 ] [Liu, G.]College of Chemistry, Chemical Engineering and Materials Science, SIP, Key Laboratory of Organic Synthesis of Jiangsu Province, Soochow University, Suzhou 215123, China
  • [ 2 ] [Hong, R.Y.]College of Chemistry, Chemical Engineering and Materials Science, SIP, Key Laboratory of Organic Synthesis of Jiangsu Province, Soochow University, Suzhou 215123, China
  • [ 3 ] [Hong, R.Y.]College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou 350002, China
  • [ 4 ] [Guo, L.]MRI Division, The First Affiliated Hospital of Soochow University, Suzhou 215007, China
  • [ 5 ] [Liu, G.H.]Resparation Department, The Affiliated Suzhou Municipal Hospital (East-section) of Nanjing Medical University, Suzhou 215001, China
  • [ 6 ] [Feng, B.]College of Chemistry, Chemical Engineering and Materials Science, SIP, Key Laboratory of Organic Synthesis of Jiangsu Province, Soochow University, Suzhou 215123, China
  • [ 7 ] [Li, Y.G.]MRI Division, The First Affiliated Hospital of Soochow University, Suzhou 215007, China

Reprint 's Address:

  • [hong, r.y.]college of chemistry and chemical engineering, fuzhou university, fuzhou 350002, china;;[hong, r.y.]college of chemistry, chemical engineering and materials science, sip, key laboratory of organic synthesis of jiangsu province, soochow university, suzhou 215123, china

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Source :

Colloids and Surfaces A: Physicochemical and Engineering Aspects

ISSN: 0927-7757

Year: 2011

Issue: 1-3

Volume: 380

Page: 327-333

2 . 2 3 6

JCR@2011

4 . 9 0 0

JCR@2023

JCR Journal Grade:2

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 0

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