A　multiple-metal　(Ni-Cu-Mn-K/Al2O3)　catalyst　was　prepared　by　impregnated　method.　The　effects　of　technology　parameters　and　global　kinetics　on　the　water　gas　shift　reaction　using　this　catalyst　were　investigated.　The　results　of　technology　parameters　showed　that　the　increase　of　the　vapor/gas　(v/g)　radio　enhanced　CO　conversion,　the　optimum　v/g　radio　for　was　gas　shift　reaction　was　from　0.8　to　1.5.　The　space　velocity　had　only　a　negligible　effect　on　the　CO　conversion,　revealing　a　good　operating　flexibility　for　the　catalyst　in　the　water　gas　shift　reaction　process.　With　the　reaction　temperature　rising,　there　was　an　extreme　operating　temperature　for　CO　conversion　around　400°C.　Its　global　kinetics　was　also　investigated　in　an　internal-circulation　gradientless　reactor,　and　a　power　law　type　global　kinetics　model　for　the　water　gas　shift　reaction　using　this　catalyst　was　regressed　by　the　non-linear　square　method.　The　results　based　on　the　global　kinetics　model　were　in　very　good　agreement　with　the　experimental　data.　It　is　demonstrated　that　the　model　is　liable　and　suitable.