Electrochemical sensors for L-Tryptophan based on molecularly imprinted polymers - Details

author：

Xu, Wen (Xu, Wen.) ^[1] | Li, Xiao (Li, Xiao.) ^[2] (Scholars：李晓) | Zhang, Weiying (Zhang, Weiying.) ^[3] (Scholars：张卫英) | Ying, Xiaoguang (Ying, Xiaoguang.) ^[4] (Scholars：英晓光)

Indexed by：

EI Scopus

Abstract：

A　novel　sensing　element　for　direct　detection　of　L-Tryptophan　(L-Trp)　in　human　serum　was　proposed　by　combination　of　electrochemical　transduction　and　molecular　imprinting　technique.　The　sensing　element　was　prepared　by　electropolymerization　of　o-phenylenediamine　(o-PD)　on　the　gold　electrode　in　the　presence　of　template　L-Trp.　The　electrochemical　property　of　the　sensor　was　characterized　by　differential　pulse　voltammetry　(DPV).　The　linear　response　range　of　the　sensor　for　L-Trp　concentration　was　1×10-8　mol/L∼21×10-8　mol/L　with　a　detection　limit　of　0.3×10-8　mol/L.　The　results　show　that　this　approach　has　the　potential　to　generate　a　universal　inexpensive　assay　methodology　of　high　sensitivity,　specificity　and　simplicity　to　detect　L-Trp.　©　(2012)　Trans　Tech　Publications.

Keyword：

Amino acids Biosynthesis Composite materials Electrochemical sensors Electropolymerization Molecular modeling Polymers Sensors Voltammetry

Community：

[ 1 ] [Xu, Wen]College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou 350108, China
[ 2 ] [Li, Xiao]College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou 350108, China
[ 3 ] [Zhang, Weiying]College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou 350108, China
[ 4 ] [Ying, Xiaoguang]College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou 350108, China