Facile fabrication of microfluidic surface-enhanced raman scattering devices via lift-up lithography - Details

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Abstract：

We　describe　a　facile　and　low-cost　approach　for　a　flexibly　integrated　surface-enhanced　Raman　scattering　(SERS)　substrate　in　microfluidic　chips.　Briefly,　a　SERS　substrate　was　fabricated　by　the　electrostatic　assembling　of　gold　nanoparticles,　and　shaped　into　designed　patterns　by　subsequent　lift-up　soft　lithography.　The　SERS　micro-pattern　could　be　further　integrated　within　microfluidic　channels　conveniently.　The　resulting　microfluidic　SERS　chip　allowed　ultrasensitive　in　situ　SERS　monitoring　from　the　transparent　glass　window.　With　its　advantages　in　simplicity,　functionality　and　cost-effectiveness,　this　method　could　be　readily　expanded　into　optical　microfluidic　fabrication　for　biochemical　applications.　©　2018　The　Authors.

Keyword：

Lift-up lithography; Microfluidics; Surface-enhanced Raman scattering substrate

Community：

[ 1 ] [Wu, Y.]College of Biological Science and Engineering, Fuzhou University, Fuzhou, 350002, China
[ 2 ] [Jiang, Y.]College of Biological Science and Engineering, Fuzhou University, Fuzhou, 350002, China
[ 3 ] [Zheng, X.]State Key Laboratory of Physical Chemistry of Solid Surfaces, The MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, College of Chemistry and Chemical Engineering, Collaborative Innovation Center of Chemistry of Energy Materials, Xiamen University, Xiamen, 361005, China
[ 4 ] [Jia, S.]State Key Laboratory of Physical Chemistry of Solid Surfaces, The MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, College of Chemistry and Chemical Engineering, Collaborative Innovation Center of Chemistry of Energy Materials, Xiamen University, Xiamen, 361005, China
[ 5 ] [Zhu, Z.]State Key Laboratory of Physical Chemistry of Solid Surfaces, The MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, College of Chemistry and Chemical Engineering, Collaborative Innovation Center of Chemistry of Energy Materials, Xiamen University, Xiamen, 361005, China
[ 6 ] [Ren, B.]State Key Laboratory of Physical Chemistry of Solid Surfaces, The MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, College of Chemistry and Chemical Engineering, Collaborative Innovation Center of Chemistry of Energy Materials, Xiamen University, Xiamen, 361005, China
[ 7 ] [Ma, H.]Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, 215125, China

Reprint 's Address：

[Ren, B.]State Key Laboratory of Physical Chemistry of Solid Surfaces, The MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, College of Chemistry and Chemical Engineering, Collaborative Innovation Center of Chemistry of Energy Materials, Xiamen UniversityChina

Email：

bren@xmu.edu.cn

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Source ：

Royal Society Open Science

ISSN： 2054-5703

Year： 2018

Issue： 4

Volume： 5

2 . 5 1 5

JCR@2018

2 . 9 0 0

JCR@2023

ESI HC Threshold：395

JCR Journal Grade：2

CAS Journal Grade：3

Cited Count：

WoS CC Cited Count：

SCOPUS Cited Count： 20

ESI Highly Cited Papers on the List： 0 Unfold All

WanFang Cited Count：

Chinese Cited Count：

30 Days PV： 2

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