The　exploration　of　anode　materials　for　lithium　ion　batteries　(LIBs)　or　sodium　ion　batteries　(SIBs)　represents　a　grand　technological　challenge　to　meet　the　continuously　increased　demand　for　the　high-performance　energy　storage　market.　Here　we　report　a　facile　and　reliable　synthetic　strategy　for　in　situ　growth　of　few-layer　MoS2　nanosheets　on　reduced　graphene　oxide　(rGO)　cross-linked　hollow　carbon　spheres　(HCS)　with　formation　of　three-dimensional　(3D)　network　nanohybrids　(MoS2-rGO/HCS).　Systematic　electrochemical　studies　demonstrate,　as　an　anode　of　LIBs,　the　as-developed　MoS2-rGO/HCS　can　deliver　a　reversible　capacity　of　1145　mAh　g-1　after　100　cycles　at　0.1　A　g-1　and　a　revisible　capacity　of　753　mAh　g-1　over　1000　cycles　at　2　A　g-1.　For　SIBs,　the　as-developed　MoS2-rGO/HCS　can　also　maintain　a　reversible　capacity　of　443　mAh　g-1　at　1　A　g-1　after　500　cycles.　The　excellent　electrochemical　performance　can　be　attributed　to　the　3D　porous　structures,　in　which　the　few-layer　MoS2　nanosheets　with　expanded　interlayers　can　provide　shortened　ion　diffusion　paths　and　improved　Li+/Na+　diffusion　mobility,　and　the　hollow　porous　carbon　spheres　and　the　outside　graphene　network　are　able　to　improve　the　conductivity　and　maintain　the　structural　integrity.　©　2018　American　Chemical　Society.