It　is　imperative　to　remove　organicarsenic　acids　(OAAs)　from　water　because　they　can　convert　into　highly　toxic　inorganic　arsenic　compounds　in　natural　environment　via　biotic　and　abiotic　degradation　routes.　Herein,　seven　Zr-based　metal-organic　frameworks　(Zr-MOFs)　including　DUT-67,　UiO-66,　UiO-67,　MOF-808,　MOF-808F,　NU-1000,　NU-1000B　with　various　structures　were　screened　for　the　adsorptive　removal　of　representative　OAAs　including　p-arsanilic　acid　(ASA)　and　roxarsone　(ROX)　in　water　media.　Initial　screening　found　that　MOF-808　and　MOF-808F　have　the　largest　adsorption　capacities.　Therefore,　their　adsorption　behaviors　including　adsorption　kinetics,　isotherms,　specificity　and　effects　of　pH　were　fully　investigated.　Remarkably,　MOF-808F　had　the　second　largest　maximum　adsorption　capacities　of　ASA　(621.1　mg　g−1)　and　ROX　(709.2　mg　g−1)　among　the　reported　MOF-based　adsorbents.　In　addition,　MOF-808F　showed　excellent　selectivity　and　reusability　and　no　observable　drop　of　adsorption　efficiency　was　found　in　the　presence　of　equimolar　competing　ions　(Cl−,　OAc−　or　SO42−)　or　after　three　successive　adsorptive　runs.　By　contrast,　MOF-808　had　inferior　adsorption　specificity　and　reusability　in　spite　of　the　very　similar　structure　with　MOF-808F.　The　structure-dependent　adsorption　performances　can　be　explained　by　the　distinct　adsorptive　mechanisms,　which　were　revealed　by　zeta　potential　measurements,　X-ray　photoelectron　spectroscopy　(XPS),　and　density　functional　theory　(DFT)　calculation　etc.　The　dominant　interaction　between　MOF-808　and　ASA　was　coordination　interactions,　while　ASA　adsorption　over　MOF-808F　was　governed　by　the　synergistic　effect　of　π-π　stacking,　hydrogen　bonding,　and　electrostatic　interactions.　This　work　no　only　presented　an　excellent　adsorbent　(MOF-808F)　toward　OAAs,　but　also　revealed　the　structure　dependent　adsorption　performances/mechanisms.　©　2019　Elsevier　B.V.