Glutathione-protected　Aux　nanoclusters　uniformly　and　intimately　embedded　at　the　interface　of　CdSe　QDs　and　graphene　were　in　situ　self-transformed　to　Au　nanocrystals　(NCs)　via　a　facile　thermal　reduction　strategy.　The　inlaid　Au　NPs　substantially　accelerate　the　interfacial　directional　charge　transfer　toward　multifarious　photoreduction　catalysis　under　visible　light　irradiation.　This　journal　is　©　The　Royal　Society　of　Chemistry.