In　this　paper,　a　design　method　of　an　infusion　monitoring　device　using　a　5kg　load　cell　was　proposed,　and　a　material　object　with　a　monitoring　accuracy　of　0.1g　was　fabricated　by　this　method.　Usually,　the　use　of　load　cells　to　monitor　the　infusion　situation　will　face　a　variety　of　external　disturbances.　This　paper　ensured　that　the　correct　data　was　filtered　out　via　the　range　analysis　of　the　measured　values　and　software　filtering,　and　summed　up　all　kinds　of　errors　that　may　occur,　which　made　the　device　have　the　ability　to　judge　varieties　of　errors.　Besides,　the　selection　of　different　thresholds　in　the　range　was　explored　so　that　the　device　can　dynamically　adjust　the　threshold　according　to　different　drug　solutions,　different　rate　requirements,　and　different　infusion　sets.　Furthermore,　this　paper　proposed　the　equation　and　method　of　temperature　correction.　The　results　show　that　the　proposed　design　method　made　the　device　more　practical.　©　2019　IEEE.