Quantum　correlations　in　observables　of　multiple　systems　not　only　are　of　fundamental　interest,　but　also　play　a　key　role　in　quantum　information　processing.　As　a　signature　of　these　correlations,　the　violation　of　Bell　inequalities　has　not　been　demonstrated　with　multipartite　hybrid　entanglement　involving　both　continuous　and　discrete　variables.　Here　we　create　a　five-partite　entangled　state　with　three　superconducting　transmon　qubits　and　two　photonic　qubits,　each　encoded　in　the　mesoscopic　field　of　a　microwave　cavity.　We　reveal　the　quantum　correlations　among　these　distinct　elements　by　joint　Wigner　tomography　of　the　two　cavity　fields　conditional　on　the　detection　of　the　qubits　and　by　test　of　a　five-partite　Bell　inequality.　The　measured　Bell　signal　is　8.381±0.038,　surpassing　the　bound　of　8　for　a　four-partite　entanglement　imposed　by　quantum　correlations　by　10　standard　deviations,　demonstrating　the　genuine　five-partite　entanglement　in　a　hybrid　quantum　system.　©　2020　American　Physical　Society.