In　order　to　implement　the　multi-scale　model　to　optimize　the　structure　of　vapor-liquid　mass　transfer　layer,　vapor　and　liquid　mass　transfer　coefficients　that　embrace　the　effects　of　structure　parameters　of　mass　transfer　layer　should　be　obtained　in　advance.　In　the　study,　the　influences　of　four　structure　parameters　on　mass　transfer　performance　were　studied　by　the　tracer　method.　Moreover,　the　corresponding　mass　transfer　coefficients　were　correlated.　By　comparing　with　the　experimental　data　of　different　types　of　structured　catalytic　packings,　it　has　been　found　that　the　correlations　exhibit　good　universality.　Furthermore,　the　correlations　were　applied　to　the　non-equilibrium　model　for　the　hydrolysis　of　methyl　acetate　(MA),　so　as　to　investigate　the　influences　of　four　structure　parameters　on　catalytic　distillation　process.　The　results　indicated　that　wavy　height　and　the　area　ratio　of　mass　transfer　layer　to　catalyst　layer　have　more　significant　influences　on　the　conversion　of　MA　than　inclined　angle　and　base　length.　©　2019　Elsevier　Ltd