Three　CeO2　materials　were　prepared　with　precipitation　(A),　hydrothermal　route　(B)　and　citrate　sol-gel　(C)　methods,　and　then　used　as　the　support　of　CuO/CeO2　catalysts,　which　were　prepared　by　a　deposition-precipitation　method　and　examined　with　respect　to　their　catalytic　activities　for　the　water-gas　shift　(WGS)　reaction.　The　effect　of　the　CeO2　support　prepared　with　different　methods　on　the　structural　properties,　redox　properties,　catalytic　activities　and　stabilities　of　the　CuO/CeO2　catalysts　for　the　WGS　reaction　was　studied　in　detail　using　N2　physics　adsorption　(Brunauer-　Emmett-Teller,　BET),　powder　X-ray　diffraction　(PXRD),　in　situ　PXRD,　H2-temperature　programmed　reduction　(H2-TPR)　and　cyclic　voltammetry　(CV).　Results　indicate　that　both　the　catalytic　activities　and　stabilities　of　the　as-synthesized　CuO/CeO2　catalysts　are　CuO/CeO2-A>CuO/CeO2-B>CuO/CeO2-C.　Characterization　results　show　that　catalytic　activities　of　the　CuO/CeO2　catalysts　are　closely　related　to　the　crystal　size　of　CuO　particles,　the　microstrain　value　for　CuO,　and　the　amount　of　moderate　size　copper　oxides　(crystalline)　that　interacted　with　ceria.　These　factors　depend　greatly　on　the　thermal　stabilities　of　the　CeO2　supports.　CV　results　suggest　that　the　peak　area　of　Cu2+↔Cu0　redox　reaction　decreased　from　the　first　to　the　second　cycle,　indicating　that　the　electrode　reaction　is　irreversible　and　this　might　be　a　reason　for　the　observed　deactivation　of　CuO/CeO2　catalysts　after　the　temperature　cycle.　©　Editorial　office　of　Acta　Physico-Chimica　Sinica.