A　series　of　HPW/Cs-HMS　catalysts　with　different　HPW　loadings　(the　molar　ratio　of　Cs　to　HPW　is　1.5)　were　prepared　by　the　equal　volume　incipient　impregnation　method,　in　which　n-butanol　was　used　as　solvent,　and　the　carrier,　cesium-containing　molecular　sieve　(Cs-HMS),　was　synthesized　by　the　technique　of　doped　atoms　with　dodecylamine　(DDA)　as　template.　The　HPW/Cs-HMS　catalysts　were　characterized　by　various　means.　The　influences　of　HPW　loadings　on　the　structural　properties　and　catalytic　performance　of　HPW/Cs-HMS　for　methyl　acetate　hydrolysis　were　investigated.　The　results　showed　that　with　the　increase　of　HPW　loadings　the　mesoporous　structural　order,　the　BET　surface　area　and　the　pore　volume　of　molecular　sieve　drastically　decreased,　the　structure　and　shape　of　HPW/Cs-HMS　catalyst　turned　from　a　short-range-ordering　mesopore　and　a　hollow　micrometric　spherical　shape　to　the　disordered　micropore　and　the　flaky　shape　gradually.　The　optimal　HPW　loading　of　HPW/Cs-HMS　catalyst　for　methyl　acetate　hydrolysis　was　40%.　The　hydrolysis　conversion　of　methyl　acetate　on　40%HPW/Cs-HMS　reached　45.7%　in　2　h　at　55°C　with　the　conditions　that　H2O　was　9　g,　m(H2O)/m(MeOAc)=1,　and　the　total　HPW　loading　was　1　g,　while　under　the　conditions　that　MeOAc　was　18　g,　H2O　was　4.5　g　and　the　total　HPW　loading　was　0.5　g,　the　hydrolysis　conversion　of　methyl　acetate　reached　21.8%　in　0.5　h　at　100°C,　which　had　an　enhancement　of　5%　compared　to　NKC-9　resin.　The　activity　of　40%HPW/Cs-HMS　was　not　changed　after　5　cycle　uses,　keeping　20.8%,　but　the　conversion　of　methyl　acetate　on　NKC-9　decreased　gradually　with　the　increase　of　cycle　uses.