An electrochemiluminescent biosensor for uric acid based on the electrochemiluminescence of bis-[3,4,6-trichloro-2-(pentyloxycarbonyl)-phenyl] oxalate on an ITO electrode modified by an electropolymerized nickel phthalocyanine film - Details

author：

Lin, Z. (Lin, Z..) ^[1] | Chen, Z. (Chen, Z..) ^[2] | Liu, Y. (Liu, Y..) ^[3] | Wang, J. (Wang, J..) ^[4] | Chen, G. (Chen, G..) ^[5]

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Abstract：

Nickel(II)　tetrasulfophthalo-cyanine　(NiTSPc)　could　be　electrodeposited　onto　an　indium　tin　oxide　(ITO)　electrode　to　form　an　electropolymerization　film　of　NiTSPc.　The　electrochemiluminescent　(ECL)　behavior　of　bis-[3,4,6-trichloro-2-　(pentyloxy-carbonyl)-phenyl]　oxalate　(BTPPO)　on　this　modified　electrode　was　investigated　in　detail.　The　emission　of　ECL　of　BTPPO　can　be　greatly　enhanced　by　hydrogen　peroxide　at　this　modified　electrode.　Thus,　a　new　ECL　biosensor　for　uric　acid　was　developed　based　on　the　enzymatic　reaction　of　uric　acid　in　the　presence　of　uricase　to　produce　H2O2.　The　developed　sensor　has　been　used　to　detect　uric　acid　in　real　serum　samples,　and　the　results　compared　well　with　those　obtained　by　the　routine　method.　©　The　Royal　Society　of　Chemistry.

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[ 1 ] [Lin, Z.]Min. of Educ. Key Lab. of Analysis and Detection Technology for Food Safety (Fuzhou University), Department of Chemistry, Fuzhou University, Fuzhou, Fujian, 350002, China
[ 2 ] [Chen, Z.]Min. of Educ. Key Lab. of Analysis and Detection Technology for Food Safety (Fuzhou University), Department of Chemistry, Fuzhou University, Fuzhou, Fujian, 350002, China
[ 3 ] [Liu, Y.]Min. of Educ. Key Lab. of Analysis and Detection Technology for Food Safety (Fuzhou University), Department of Chemistry, Fuzhou University, Fuzhou, Fujian, 350002, China
[ 4 ] [Wang, J.]Min. of Educ. Key Lab. of Analysis and Detection Technology for Food Safety (Fuzhou University), Department of Chemistry, Fuzhou University, Fuzhou, Fujian, 350002, China
[ 5 ] [Chen, G.]Min. of Educ. Key Lab. of Analysis and Detection Technology for Food Safety (Fuzhou University), Department of Chemistry, Fuzhou University, Fuzhou, Fujian, 350002, China

Reprint 's Address：

[Chen, G.]Min. of Educ. Key Lab. of Analysis and Detection Technology for Food Safety (Fuzhou University), Department of Chemistry, Fuzhou University, Fuzhou, Fujian, 350002, China

Email：

gnchen@fzu.edu.cn

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Source ：

Analyst

ISSN： 0003-2654

Year： 2008

Issue： 6

Volume： 133

Page： 797-801

3 . 7 6 1

JCR@2008

3 . 6 0 0

JCR@2023

JCR Journal Grade：1

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SCOPUS Cited Count：

ESI Highly Cited Papers on the List： 0 Unfold All

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Chinese Cited Count：

30 Days PV： 3

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