Plant Polyphenol-Assisted Green Synthesis of Hollow CoPt Alloy Nanoparticles for Dual-Modality Imaging Guided Photothermal Therapy - Details

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Abstract：

Theranostic　nanomedicines　that　integrate　diagnostic　and　therapeutic　moieties　into　a　single　nanoscale　platform　are　playing　an　increasingly　important　role　in　fighting　cancer.　Here,　a　facile　and　green　synthetic　strategy　for　hollow　CoPt　alloy　nanoparticles　(HCPA-NPs)　using　plant　polyphenols　as　assisted　agents　is　reported　for　the　first　time.　This　novel　strategy　enables　size-controlled　synthesis　of　HCPA-NPs　through　the　control　of　the　molecular　sizes　of　polyphenols.　It　is　also　a　versatile　strategy　for　synthesizing　other　hollow　alloy　nanoparticles　with　various　metal　compositions　due　to　the　diverse　metal-chelating　ability　of　the　polyphenols.　Further　studies　show　that　HCPA-NPs　have　good　biocompatibility　and　can　be　successfully　implemented　for　magnetic　resonance　and　photoacoustic　dual-modal　imaging　guided　photothermal　therapy.　This　work　brings　new　insights　for　the　green　synthesis　of　hollow　nanoparticles　and　extends　these　biocompatible　nanoparticles　for　theranostic　applications.　©　2016　WILEY-VCH　Verlag　GmbH　&　Co.　KGaA,　Weinheim.

Keyword：

alloy; magnetic imaging; photoacoustic imaging; photothermal therapy

Community：

[ 1 ] [Song, X.-R.]Key Lab of Analysis and Detection Technology for Food Safety of the MOE, State Key Laboratory of Photocatalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fuzhou, 350108, China
[ 2 ] [Yu, S.-X.]Key Lab of Analysis and Detection Technology for Food Safety of the MOE, State Key Laboratory of Photocatalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fuzhou, 350108, China
[ 3 ] [Jin, G.-X.]Key Lab of Analysis and Detection Technology for Food Safety of the MOE, State Key Laboratory of Photocatalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fuzhou, 350108, China
[ 4 ] [Wang, X.]State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361005, China
[ 5 ] [Chen, J.]Key Lab of Analysis and Detection Technology for Food Safety of the MOE, State Key Laboratory of Photocatalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fuzhou, 350108, China
[ 6 ] [Li, J.]Key Lab of Analysis and Detection Technology for Food Safety of the MOE, State Key Laboratory of Photocatalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fuzhou, 350108, China
[ 7 ] [Liu, G.]State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, 361005, China
[ 8 ] [Yang, H.-H.]Key Lab of Analysis and Detection Technology for Food Safety of the MOE, State Key Laboratory of Photocatalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fuzhou, 350108, China

Reprint 's Address：

[Liu, G.]State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen UniversityChina

Email：

gangliu.cmitm@xmu.edu.cn

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Small

ISSN： 1613-6810

Year： 2016

Issue： 11

Volume： 12

Page： 1506-1513

8 . 6 4 3

JCR@2016

1 3 . 0 0 0

JCR@2023

ESI HC Threshold：324

JCR Journal Grade：1

CAS Journal Grade：1

Cited Count：

WoS CC Cited Count：

SCOPUS Cited Count： 59

ESI Highly Cited Papers on the List： 0 Unfold All

WanFang Cited Count：

Chinese Cited Count：

30 Days PV： 0

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