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author:

Goryacheva, I.Y. (Goryacheva, I.Y..) [1] | Speranskaya, E.S. (Speranskaya, E.S..) [2] | Goftman, V.V. (Goftman, V.V..) [3] | Tang, D. (Tang, D..) [4] | De, Saeger, S. (De, Saeger, S..) [5]

Indexed by:

Scopus

Abstract:

This review focuses on selected examples of multiloaded quantum-dot (QD) nanocomposites as novel concepts and promising labels for bioimaging and analysis. As bright, excellent, 10-nm-sized labels, providing high-intensity signal, QDs can reach higher levels when multiloaded into a single biocompatible nanocontainer. QD-containing nanocomposites combine the properties of both materials (i.e., luminescent and electrochemical characteristics of the entrapped QDs and permeability, solubility, reactivity or biocompatibility of the carrier). Approaches described include multiple QD-containing nanocomposites with different carriers - organic (dendrimers and layer-by-layer hollow microcapsules), inorganic (carbon nanotubes and silica nanoparticles) and of a combined nature. We also consider and discuss promising applications in bioanalysis. © 2014 Elsevier B.V.

Keyword:

Bioanalysis; Bioimaging; Biolabeling; Enhanced label; Immunoassay; Multifunctional particle; Nanoparticle; Nanostructure; Quantum dot; Synthesis

Community:

  • [ 1 ] [Goryacheva, I.Y.]Department of General and Inorganic Chemistry, Chemistry Institute, Saratov State University, Astrakhanskaya 83, Saratov, 410012, Russian Federation
  • [ 2 ] [Speranskaya, E.S.]Department of General and Inorganic Chemistry, Chemistry Institute, Saratov State University, Astrakhanskaya 83, Saratov, 410012, Russian Federation
  • [ 3 ] [Speranskaya, E.S.]Laboratory of Food Analysis, Faculty of Pharmaceutical Sciences, Ghent University, Harelbekestraat 72, Ghent, 9000, Belgium
  • [ 4 ] [Goftman, V.V.]Department of General and Inorganic Chemistry, Chemistry Institute, Saratov State University, Astrakhanskaya 83, Saratov, 410012, Russian Federation
  • [ 5 ] [Goftman, V.V.]Laboratory of Food Analysis, Faculty of Pharmaceutical Sciences, Ghent University, Harelbekestraat 72, Ghent, 9000, Belgium
  • [ 6 ] [Tang, D.]Key Laboratory of Analysis and Detection for Food Safety, Fuzhou University, Fuzhou, 350108, China
  • [ 7 ] [De Saeger, S.]Laboratory of Food Analysis, Faculty of Pharmaceutical Sciences, Ghent University, Harelbekestraat 72, Ghent, 9000, Belgium

Reprint 's Address:

  • [Goryacheva, I.Y.]Department of General and Inorganic Chemistry, Chemistry Institute, Saratov State University, Astrakhanskaya 83, Russian Federation

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Source :

TrAC - Trends in Analytical Chemistry

ISSN: 0165-9936

Year: 2015

Volume: 66

Page: 53-62

7 . 4 8 7

JCR@2015

1 1 . 8 0 0

JCR@2023

ESI HC Threshold:265

JCR Journal Grade:1

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 0

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