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author：

Zhang, X. (Zhang, X..) [1] | Zhang, J. (Zhang, J..) [2] | Wu, D. (Wu, D..) [3] | Liu, Z. (Liu, Z..) [4] | Cai, S. (Cai, S..) [5] | Chen, M. (Chen, M..) [6] | Zhao, Y. (Zhao, Y..) [7] | Li, C. (Li, C..) [8] | Yang, H. (Yang, H..) [9] | Chen, J. (Chen, J..) [10]

Indexed by：

Scopus

Abstract：

Locked　nucleic　acid　(LNA)　is　applied　in　toehold-mediated　strand　displacement　reaction　(TMSDR)　to　develop　a　junction-probe　electrochemiluminescence　(ECL)　biosensor　for　single-nucleotide　polymorphism　(SNP)　detection　in　the　BRCA1　gene　related　to　breast　cancer.　More　than　65-fold　signal　difference　can　be　observed　with　perfectly　matched　target　sequence　to　single-base　mismatched　sequence　under　the　same　conditions,　indicating　good　selectivity　of　the　ECL　biosensor.　©　2014　the　Partner　Organisations.

Keyword：

Community：

  • [ 1 ] [Zhang, X.]Department of Pharmaceutical Analysis, Faculty of Pharmacy, Fujian Medical University, Fuzhou, Fujian, 350108, China
  • [ 2 ] [Zhang, J.]The Ministry of Education Key Laboratory of Biopesticide and Chemical Biology, College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, Fujian, 350002, China
  • [ 3 ] [Wu, D.]Department of Pharmaceutical Analysis, Faculty of Pharmacy, Fujian Medical University, Fuzhou, Fujian, 350108, China
  • [ 4 ] [Liu, Z.]Department of Pharmaceutical Analysis, Faculty of Pharmacy, Fujian Medical University, Fuzhou, Fujian, 350108, China
  • [ 5 ] [Cai, S.]Department of Pharmaceutical Analysis, Faculty of Pharmacy, Fujian Medical University, Fuzhou, Fujian, 350108, China
  • [ 6 ] [Chen, M.]Department of Pharmaceutical Analysis, Faculty of Pharmacy, Fujian Medical University, Fuzhou, Fujian, 350108, China
  • [ 7 ] [Zhao, Y.]Department of Pharmaceutical Analysis, Faculty of Pharmacy, Fujian Medical University, Fuzhou, Fujian, 350108, China
  • [ 8 ] [Li, C.]Department of Pharmaceutical Analysis, Faculty of Pharmacy, Fujian Medical University, Fuzhou, Fujian, 350108, China
  • [ 9 ] [Yang, H.]Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, Fuzhou University, Fuzhou, Fujian, 350002, China
  • [ 10 ] [Chen, J.]Department of Pharmaceutical Analysis, Faculty of Pharmacy, Fujian Medical University, Fuzhou, Fujian, 350108, China

Reprint 's Address：

  • [Zhang, J.]The Ministry of Education Key Laboratory of Biopesticide and Chemical Biology, College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, Fujian, 350002, China

Email：


1601225385@qq.com
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Source ：

Analyst

ISSN： 0003-2654

Year： 2014

Issue： 23

Volume： 139

Page： 6109-6112

4 . 1 0 7

JCR@2014

3 . 6 0 0

JCR@2023

ESI HC Threshold：268

JCR Journal Grade：1

CAS Journal Grade：2

Cited Count：

WoS CC Cited Count： 0

SCOPUS Cited Count： 11

ESI Highly Cited Papers on the List： 0 Unfold All

WanFang Cited Count：

Chinese Cited Count：

30 Days PV： 3

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