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author:

Hong, C.-Y. (Hong, C.-Y..) [1] | Chen, X. (Chen, X..) [2] | Li, J. (Li, J..) [3] | Chen, J.-H. (Chen, J.-H..) [4] | Chen, G. (Chen, G..) [5] | Yang, H.-H. (Yang, H.-H..) [6]

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Scopus

Abstract:

We have developed a simple method for direct detection of circulating microRNAs in serum by using the p19 protein-functionalized magnetic beads (PFMBs) for specific enrichment and rolling circle amplification (RCA). The detection limit for microRNAs is 1 fM. Therefore, the proposed method has the potential of being used in the analysis of circulating microRNAs and clinical diagnosis. © The Royal Society of Chemistry 2014.

Keyword:

Community:

  • [ 1 ] [Hong, C.-Y.]Key Lab. of Analysis and Detection for Food Safety of MOE and Fujian Provincial, College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou 350108, China
  • [ 2 ] [Chen, X.]Key Lab. of Analysis and Detection for Food Safety of MOE and Fujian Provincial, College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou 350108, China
  • [ 3 ] [Li, J.]Key Lab. of Analysis and Detection for Food Safety of MOE and Fujian Provincial, College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou 350108, China
  • [ 4 ] [Chen, J.-H.]Department of Pharmaceutical Analysis, Faculty of Pharmacy, Fujian Medical University, Fuzhou 350004, China
  • [ 5 ] [Chen, G.]Key Lab. of Analysis and Detection for Food Safety of MOE and Fujian Provincial, College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou 350108, China
  • [ 6 ] [Yang, H.-H.]Key Lab. of Analysis and Detection for Food Safety of MOE and Fujian Provincial, College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou 350108, China

Reprint 's Address:

  • [Chen, J.-H.]Department of Pharmaceutical Analysis, Faculty of Pharmacy, Fujian Medical University, Fuzhou 350004, China

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Source :

Chemical Communications

ISSN: 1359-7345

Year: 2014

Issue: 25

Volume: 50

Page: 3292-3295

6 . 8 3 4

JCR@2014

4 . 3 0 0

JCR@2023

ESI HC Threshold:268

JCR Journal Grade:1

CAS Journal Grade:2

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count: 41

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 0

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