A portable chemical sensor for histidine based on the strategy of click chemistry - Details

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Abstract：

A　novel　portable　chemical　sensor　is　developed　in　combination　of　the　personal　glucose　meters　(PGM)　with　click　chemistry　for　sensitive　and　selective　determination　of　histidine.　Invertase-labeled　alkynyl-DNA　can　be　modified　onto　the　surfaces　of　Streptavidin　Magnespheres　Paramagnetic　Particles　(PMPs)　through　copper(I)　catalyzed　azide-alkyne　cycloaddition　(CuAAC)　reaction　and　formed　invertase-functionalized　PMPs,　which　can　be　separated　easily.　The　presence　of　invertase　can　convert　sucrose　to　glucose　and　can　be　monitored　by　the　PGM　easily.　The　presence　of　histidine　can　inhibit　the　CuAAC,　so　the　read-out　signal　of　PGM　decreased.　The　difference　in　signals　from　the　PGM　before　and　after　addition　of　histidine　has　a　good　linear　correlation　with　the　logarithm　of　the　histidine　concentrations　in　the　range　of　0.01~100.　μM　with　a　detection　limit　of　3.4.　nM,　which　is　lower　than　those　of　many　other　chemical　sensors.　Moreover,　the　assay　of　histidine　in　milk　samples　is　demonstrated　with　satisfactory　results.　©　2013　Elsevier　B.V.

Keyword：

Click chemistry; Histidine; Invertase; Milk; Personal glucose meters

Community：

[ 1 ] [Zhou, J.]MOE Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Lab. of Analysis and Detection Technology for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, China
[ 2 ] [Xu, K.]MOE Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Lab. of Analysis and Detection Technology for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, China
[ 3 ] [Zhou, P.]MOE Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Lab. of Analysis and Detection Technology for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, China
[ 4 ] [Zheng, O.]MOE Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Lab. of Analysis and Detection Technology for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, China
[ 5 ] [Lin, Z.]MOE Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Lab. of Analysis and Detection Technology for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, China
[ 6 ] [Guo, L.]MOE Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Lab. of Analysis and Detection Technology for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, China
[ 7 ] [Qiu, B.]MOE Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Lab. of Analysis and Detection Technology for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, China
[ 8 ] [Chen, G.]MOE Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Lab. of Analysis and Detection Technology for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, China

Reprint 's Address：

[Lin, Z.]MOE Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Lab. of Analysis and Detection Technology for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, China

Email：

zylin@fzu.edu.cn

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Source ：

Biosensors and Bioelectronics

ISSN： 0956-5663

Year： 2014

Volume： 51

Page： 386-390

6 . 4 0 9

JCR@2014

1 0 . 7 0 0

JCR@2023

ESI HC Threshold：268

JCR Journal Grade：1

CAS Journal Grade：1

Cited Count：

WoS CC Cited Count： 0

SCOPUS Cited Count： 28

ESI Highly Cited Papers on the List： 0 Unfold All

WanFang Cited Count：

Chinese Cited Count：

30 Days PV： 1

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