In　this　study,　titanate　nanosheets,　nanotubes,　and　nanowires,　were　synthesized　by　hydrothermal　treatment　anatase　TiO　2　in　different　temperatures.　The　obtained　products　are　characterized　by　X-ray　powder　diffraction　(XRD),　scanning　electron　microscopy　(SEM),　transmission　electron　micrograph　(TEM)　and　Brunauer-Emmett-Teller　(BET)　nitrogen　sorption-desorption　measurement.　Then,　the　nanostructural　titanates　were　used　as　additives　for　selectively　reducing　tobacco-specific　nitrosamines　(TNSAs)　in　mainstream　cigarette　smoke　(CS)　for　the　first　time.　These　nanomaterials　exhibited　high　reduction　ability　of　TSNAs　which　was　related　to　their　intrinsic　properties.　The　N-NO　functional　group　of　TSNAs　with　a　negative　charge　would　react　with　H　+　on　the　surface　of　nanomaterials　via　chemical　absorption　and　can　be　retained　on　the　surface　of　the　titanates.　Among　these　materials,　titanate　nanowires　(TNW)　captured　more　TNSAs　owing　to　their　network　structure,　which　resulted　in　the　selective　reduction　ratio　of　TSNAs　being　improved　significantly.　Thus,　TNW　is　a　useful　additive　for　selectively　reducing　the　TSNAs　in　CS　without　changing　the　cigarette　flavor.　©　2013　The　Royal　Society　of　Chemistry.