Using　modified　bauxite　with　large　surface　area　and　mesoporous　structure　as　the　support,　a　series　of　Cu-Fe/Bauxite　catalysts　were　synthesized　with　co-precipitation　method.　The　catalysts　were　characterized　by　means　of　X-ray　fluorescence　spectrometry　(XRF),　X-ray　diffraction　(XRD),　SBET,　H2-temperature-programmed　reduction　(H2-TPR)　and　CO　temperature-programmed　desorption　(CO-TPD)　and　X-ray　photoelectron　spectroscopy　(XPS).　Their　catalytic　activity　in　water　gas　shift　(WGS)　reaction　has　also　been　studied.　The　results　indicate　that　the　WGS　reaction　activity　increases　markedly　with　increasing　the　content　of　supported　Fe2O3　and　when　the　content　of　Fe2O3　is　to　20%,　the　catalyst　exhibits　the　highest　activity.　Because　there　exists　obvious　interaction　between　supported　Fe2O3　and　CuO　to　form　composite　oxide　like　CuFe2O4　and　it　enhances　with　increase　in　Fe2O3　content.　The　interaction　promotes　the　reduction　of　Fe2O3　and　CuO　and　restrains　the　clotting　of　CuO,　and　then　the　catalytic　activity　increases.