Sensitive fluorescence biosensor for folate receptor based on terminal protection of small-molecule-linked DNA - Details

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Abstract：

Based　on　the　specific　folic　acid-folate　receptor　(FA-FR)　interaction,　macromolecular　FR　can　bind　with　FA-linked　DNA-small　molecule　chimeras,　which　can　prevent　enzymolysis　by　exonuclease　III　(Exo　III),　enabling　a　novel　fluorescence　biosensor　for　FR　to　be　developed　using　quinaldine　red　as　a　G-quadruplex-binding　probe.　©　2012　The　Royal　Society　of　Chemistry.

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[ 1 ] [Wei, X.]Department of Chemistry, Fuzhou University, Ministry of Education, Fuzhou 350002, China
[ 2 ] [Lin, W.]Yanchang Oil Field Corp. Ltd., Shanxi 718500, China
[ 3 ] [Ma, N.]Department of Chemistry, Fuzhou University, Ministry of Education, Fuzhou 350002, China
[ 4 ] [Luo, F.]Department of Chemistry, Fuzhou University, Ministry of Education, Fuzhou 350002, China
[ 5 ] [Lin, Z.]Department of Chemistry, Fuzhou University, Ministry of Education, Fuzhou 350002, China
[ 6 ] [Guo, L.]Department of Chemistry, Fuzhou University, Ministry of Education, Fuzhou 350002, China
[ 7 ] [Qiu, B.]Department of Chemistry, Fuzhou University, Ministry of Education, Fuzhou 350002, China
[ 8 ] [Chen, G.]Department of Chemistry, Fuzhou University, Ministry of Education, Fuzhou 350002, China

Reprint 's Address：

[Lin, Z.]Department of Chemistry, Fuzhou University, Ministry of Education, Fuzhou 350002, China

Email：

zylin@fzu.edu.cn

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Chemical Communications

ISSN： 1359-7345

Year： 2012

Issue： 49

Volume： 48

Page： 6184-6186

6 . 3 7 8

JCR@2012

4 . 3 0 0

JCR@2023

JCR Journal Grade：1

CAS Journal Grade：2

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ESI Highly Cited Papers on the List： 0 Unfold All

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