A　series　of　Cu/ZrO　2　catalyst　samples　with　excellent　catalytic　performance　for　low-temperature　water-gas　shift　(WGS)　reaction　were　prepared　by　a　two-step　method.　First,　pure　monoclinic　ZrO　2　support　was　prepared　by　hydrothermal　synthesis,　and　then　a　certain　amount　of　CuO　was　deposited　on　the　support　by　deposition-precipitation.　The　catalyst　samples　were　characterized　by　X-ray　diffraction,　N　2-physisorption,　H　2　temperature-programmed　reduction,　X-ray　fluorescence　elemental　analysis,　high　resolution　transmission　electron　microscopy,　and　scanning　electron　microscopy,　aiming　to　know　the　effect　of　preparation　parameters　on　the　catalytic　performance　of　these　samples.　The　relationship　between　their　catalytic　performance　and　structures　was　discussed.　The　crystalline　size　and　dispersity　of　the　Cu　particles,　texture　of　Cu/ZrO　2　catalyst　samples　as　well　as　the　interaction　between　ZrO　2　and　Cu　are　greatly　influenced　by　the　preparation　conditions,　such　as　the　CuO　amount,　precipitation　temperature,　precipitant　and　calcination　temperature.　And　the　optimal　preparation　parameters　are　ZrO　2　loaded　with　25%　CuO,　precipitation　at　65°C　with　KOH　as　precipitant,　and　calcination　at　300°C　for　2　h　purging　with　H　2.