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author：

Chen, L. (Chen, L..) [1] | Zhu, T. (Zhu, T..) [2] | Ding, Y. (Ding, Y..) [3] | Khan, I.A. (Khan, I.A..) [4] | Gu, Q. (Gu, Q..) [5] | Li, D. (Li, D..) [6]

Indexed by：

Scopus

Abstract：

A　novel　sorbicillinoid　named　sorbiterrin　A　(1),　possessing　an　unprecedented　skeleton　was　isolated　from　a　marine　sediment　derived　fungus　Penicillium　terrestre.　The　structure　including　absolute　stereochemistries　was　elucidated　by　analysis　of　NMR,　MS　data　and　TDDFT　CD　calculations.　Sorbiterrin　A　showed　moderate　acetylcholinesterase　(AChE)　inhibitory　effect　with　IC　50　25　μg/mL.　©　2011　Elsevier　Ltd.　All　rights　reserved.

Keyword：

Marine derived fungus; Penicillium terrestre; Sorbicillinoid

Community：

  • [ 1 ] [Chen, L.]Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, 5 Yushan Road, Qingdao, Shandong 266003, China
  • [ 2 ] [Chen, L.]Institute of Biomedical and Pharmaceutical Technology, Fuzhou University, 2 Xueyuan Road, Fuzhou, Fujian 350002, China
  • [ 3 ] [Zhu, T.]Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, 5 Yushan Road, Qingdao, Shandong 266003, China
  • [ 4 ] [Ding, Y.]Department of Pharmacognosy, School of Pharmacy, University of Mississippi, MS 38677, United States
  • [ 5 ] [Khan, I.A.]Department of Pharmacognosy, School of Pharmacy, University of Mississippi, MS 38677, United States
  • [ 6 ] [Gu, Q.]Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, 5 Yushan Road, Qingdao, Shandong 266003, China
  • [ 7 ] [Li, D.]Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, 5 Yushan Road, Qingdao, Shandong 266003, China

Reprint 's Address：

  • [Khan, I.A.]Department of Pharmacognosy, School of Pharmacy, University of Mississippi, MS 38677, United States

Email：


ikhan@olemiss.edu
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Source ：

Tetrahedron Letters

ISSN： 0040-4039

Year： 2012

Issue： 3

Volume： 53

Page： 325-328

2 . 3 9 7

JCR@2012

1 . 5 0 0

JCR@2023

JCR Journal Grade：2

CAS Journal Grade：3

Cited Count：

WoS CC Cited Count：

SCOPUS Cited Count： 27

ESI Highly Cited Papers on the List： 0 Unfold All

WanFang Cited Count：

Chinese Cited Count：

30 Days PV： 2

Affiliated Colleges：

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