Electrochemical behaviors of diethylstilbestrol and its application in pharmacokinetics - Details

author：

Bin, Q. (Bin, Q..) ^[1] | Wei, W. (Wei, W..) ^[2] | Chi, Y. (Chi, Y..) ^[3] | Chen, G. (Chen, G..) ^[4]

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Abstract：

The　electrochemical　behaviors　of　diethylstilbestrol　(DES)　at　a　glassy　carbon　electrode　were　investigated　by　cyclic　voltammetry,　linear　sweep　voltammetry,　and　differential　pulse　voltammetry　(DPV).　Based　on　these,　a　sensitive　and　selective　DPV　method　was　developed　for　determination　of　DES.　The　linear　response　range　of　DES　is　1.0　×　10　-4-2.0　×　10　-6　mol/L　and　the　detection　limit　was　8.0　×　10　-8　mol/L.　The　developed　method　has　been　used　for　the　pharmacokinetics　of　DES　in　rabbit　blood　plasma.　©　2004　Elsevier　Inc.　All　rights　reserved.

Keyword：

Diethylstilbestrol; Electrochemistry; Pharmacokinetics

Community：

[ 1 ] [Bin, Q.]Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, China, China
[ 2 ] [Wei, W.]Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, China, China
[ 3 ] [Chi, Y.]Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, China, China
[ 4 ] [Chen, G.]Department of Chemistry, Fuzhou University, Fuzhou, Fujian 350002, China, China

Reprint 's Address：

Email：

gnchen@fzu.edu.cn

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Source ：

Analytical Biochemistry

ISSN： 0003-2697

Year： 2005

Issue： 2

Volume： 336

Page： 196-201

2 . 6 7

JCR@2005

2 . 6 0 0

JCR@2023

JCR Journal Grade：1

Cited Count：

WoS CC Cited Count：

SCOPUS Cited Count： 22

ESI Highly Cited Papers on the List： 0 Unfold All

WanFang Cited Count：

Chinese Cited Count：

30 Days PV： 1

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