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Abstract:
通过比较不同类型阴离子交换树脂的吸附性能,筛选出对(R)-扁桃酸富集率高、杂质吸附率较低的H401阴离子交换树脂。最适动态吸附条件为:上柱液pH6.0~6.5,流速1.0BV/h;最适动态洗脱条件为:洗脱液为1.0%盐酸,洗脱流速0.5BV/h。优化条件下,发酵液中(R)-扁桃酸的总提取率为95%,最终产物的纯度达95%,ee值98.5%。——
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中国医药工业杂志
Year: 2007
Issue: 08
Page: 555-557
Cited Count:
WoS CC Cited Count: 0
SCOPUS Cited Count:
ESI Highly Cited Papers on the List: 0 Unfold All
WanFang Cited Count:
Chinese Cited Count:
30 Days PV: 1
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