The　malachite　green　(MG)　has　been　widely　used　in　the　aquaculture　and　textile　industry　as　drugs　and　dyes,　respectively.　In　recent　years,　it　has　been　found　that　MG　has　side　effects　such　as　carcinogenicity,　teratogenicity　and　mutagenesis.　So　it　becomes　particularly　important　to　degrade　MG　for　these　industries.　In　this　paper,　a　set　of　equipment　using　FTO　conductive　glass　was　developed　for　degradation　of　MG.　Several　factors　affecting　the　efficiency　of　electrochemical　degradation,　including　the　solution　of　pH,　electrolyte,　applied　current　density　and　degradation　time　were　investigated.　Based　on　the　results　of　single-factor　experiment,　the　response　surface　methodology　(RSM)　was　used　for　optimal　conditions.　The　degradation　rate　of　MG　reaches　above　98%　by　electrolysis　in　6.56　g/L　NaCl　(pH　8.84)　solution　with　current　density　as　8.61　mA/cm(2)　for　20　min.　The　degradation　process　was　preliminarily　investigated　by　ultraviolet-visible　(UV-vis)　spectroscopy,　fluorescence　spectrometry,　and　total　organic　carbon　analysis.　The　equipment　and　operation　is　simple,　therefore　could　be　used　for　the　degradation　of　wastewater　yielded　during　production.