Perfluorooctanoic　acid　doped　polyaniline　(PFOA/PANI)　nanoparticles　were　successfully　prepared　through　ultrasonication-assisted　oxidation　polymerization.　The　prepared　PFOA/PANI　nanoparticles　exhibited　high　hydrophobicity　and　good　dispersibility　in　ethanol,　which　could　uniformly　distribute　in　epoxy　resin　(EP)　coatings　to　enhance　their　anti-penetrant　efficiency　towards　corrosive　media.　The　corrosion　protection　properties　of　PANIcontained　coatings　on　Q215　steel　were　evaluated　and　compared　through　electrochemical　impedance　spectroscopy　measurements　in　brine.　The　experimental　results　demonstrated　the　PFOA/PANI/EP　coatings　possessed　higher　corrosion　performance　than　the　EP　coatings　and　HCl-doped　PANI-contained　EP　coatings.　Besides,　dedoped　PFOA　molecules　from　PFOA/PANI　nanoparticles　can　be　adsorbed　on　the　surface　of　steel　to　form　a　hydrophobic　corrosion　inhibition　layer,　which　further　improves　the　corrosion　resistance.　The　impedance　of　PFOA/PANI/EP　coatings　continuously　increased　after　the　coatings　were　immersed　in　brine　for　more　than　2　days,　and　the　impedance　modulus　at　0.01　Hz　was　higher　than　6　x　108　omega.cm2　after　9　days.　The　novel　method　for　the　preparation　of　hydrophobic　PANI　nanoparticles　proposed　in　this　work　may　provide　new　ideas　and　methods　for　developing　more　high-performance　anti-corrosion　materials　and　promoting　their　applications　in　corrosion　protection.