Photocatalytic　ozonation　technique　for　wastewater　treatment　has　received　much　attention　for　their　efficient　capability　in　the　mineralization　of　persistent　organic　pollutants.　In　this　study,　nanostructured　Bi2WO6　was　prepared　by　hydrothermal　method　and　applied　in　the　photocatalytic　ozonation　process　for　tetracycline　hydrochloride　(TCH)　degradation　under　simulated　solar　light　irradiation.　Bi2WO6　triggered　an　effective　synergy　between　photocatalysis　and　ozonation,　and　it　showed　a　good　activity　and　adaptability　in　the　degradation　of　organic　compounds.　Besides,　the　influence　of　experimental　factors　on　the　total　organic　carbon　removal　(including　catalyst　dosage,　ozone　concentration,　initial　pH,　reaction　temperature　and　coexisting　ions)　was　also　investigated　comprehensively.　Spin-trapping　electron　paramagnetic　resonance　measurements　and　quenching　experiments　demonstrated　that　[rad]O2−,　[rad]OH,　1O2　and　h+　contributed　to　TCH　degradation.　The　possible　degradation　pathways　of　TCH　were　proposed　by　identifying　the　intermediates　with　liquid　chromatography-mass　spectroscopy.　©　2021　Elsevier　Ltd