Sensory　adaptation　is　an　essential　function　for　humans　to　live　on　the　earth.　Herein,　a　hybrid　synaptic　phototransistor　based　on　the　mixed-halide　perovskite/organic　semiconductor　film　is　reported.　This　hybrid　phototransistor　achieves　photosensitive　performance　including　a　high　photoresponsivity　over　4　×　103　A/W　and　an　excellent　specific　detectivity　of　2.8　×　1016　Jones.　Due　to　the　photoinduced　halide-ion　segregation　of　the　mixed-halide　perovskites　and　their　slow　recovery　properties,　the　experience-history-dependent　sensory　adaptation　behavior　can　be　mimicked.　Moreover,　the　light　pulse　width,　intensity,　light　wavelength,　and　gate　bias　can　be　used　to　regulate　the　adaptation　processes　to　improve　its　adaptability　and　perceptibility　in　different　environments.　The　CsPbBrxI3-x/organic　semiconductor　hybrid　films　produced　by　spin　coating　are　beneficial　to　large-scale　fabrication.　This　study　fabricates　a　novel　solution-processable　light-stimulated　synapse　based　on　inorganic　perovskites　for　mimicking　the　human　sensory　adaptation　that　makes　it　possible　to　approach　artificial　neural　sensory　systems.　©　2021　American　Chemical　Society.