Currently,　Tetrabromobisphenol　A　(TBBPA)　has　been　regarded　as　an　emerging　organic　pollutant　and　efficient　TBBPA　elimination　technology　has　been　attracting　increasing　attention.　In　this　work,　a　novel　photocatalyst,　MoS2/SnIn4S8,　was　synthesized　through　hydrothermal　method　by　introducing　few-layer　MoS2　nanosheets　and　then　employed　to　establish　an　integrated　photocatalytic　reduction/oxidation　system　for　the　remediation　of　TBBPA　under　visible　light.　The　characterization　results　demonstrated　that　the　few-layer　MoS2　nanosheets　were　well　combined　with　SnIn4S8　and　significantly　lowered　the　recombination　rate　of　the　photo-induced　electron　and　holes,　leading　to　outstanding　photocatalytic　performance　of　MoS2/SnIn4S8　composite.　Besides,　the　MoS2/SnIn4S8　composite　also　exhibited　excellent　reusability　(over　10　runs)　and　stability.　The　TBBPA　degradation　experiments　showed　that　the　integrated　photocatalytic　reduction/oxidation　system　was　able　to　completely　degrade　TBBPA　and　mineralize　its　byproducts　(60.2　±　2.9%).　In　the　photocatalytic　reduction,　due　to　the　cleavage　of　C–Br　bonds　by　photo-induced　electrons,　TBBPA　underwent　stepwise　debromination　and　finally　transferred　into　BPA　in　6　h.　In　the　following　photocatalytic　oxidation,　under　the　attack　of　reactive　oxygen　species　(1O2,　h+,[rad]OH　and　[rad]O2−),　BPA　was　first　decomposed　into　aromatic　products　(such　as　phenol,　benzoic　acid,　p-hydroxybenzyl　alcohol　and　so　on)　via　C–C　bond　cracking　and　hydroxylation,　and　then　further　oxidized　into　organic　acids　like　maleic　acid　and　muconic　acid　through　ring-opening,　and　finally　mineralized　into　CO2　and　H2O.　What　was　noteworthy　was　that　the　final　effluent　from　the　photocatalytic　reduction/oxidation　system　showed　no　toxicity　to　the　luminescent　bacteria.　©　2021　Elsevier　Ltd