Origami　engineering　as　an　interdisciplinary　subject　brings　thriving　progress　of　mechanisms　innovation.　In　this　paper,　a　construction　approach　from　origami　to　multiple　spherical-integrated　mechanisms　is　proposed　and　subtly　sets　up　the　bridge　between　origami　and　Bennett　linkage,　Bricard　linkage.　Subsequently,　the　attention　is　drawn　to　a　special　origami-inspired　integrated　8R　kinematotropic　metamorphic　mechanism.　The　paper　applies　screw　theory　to　illustrating　the　reconfigurability　of　singular　configurations　with　distinct　parametric　constraints　in　the　8R　mechanism.　Two　overconstrained　linkages,　a　4R　linkage　and　a　6R　linkage,　are　evolved　under　peculiar　geometrical　constraints　respectively.　Furthermore,　the　kaleidocycle　and　deployable　properties　of　the　8R　mechanism　are　revealed.　The　paper　hence　not　only　presents　an　interesting　work　extracted　from　origami　but　also　sheds　light　on　the　promising　investigation　about　the　intersection　of　distinct　types　of　reconfigurable　mechanisms.　Finally,　by　using　the　kinematotropic　metamorphic　8R　mechanism　as　the　reconfigurable　trunk,　a　novel　quadruped　robot　is　built　and　its　characteristics　will　be　investigated　in　future　research.　©　2021