Laver　is　one　of　the　major　arsenic　contributors　to　human　diets.　The　study　on　metabolic　and　residual　characteristic　of　each　arsenic　species　contained　in　laver　is　important　to　scientifically　assess　the　intake　risk　of　arsenic　in　the　laver.　The　metabolic　and　residual　characteristic　of　main　arsenic　species　in　laver,　namely　arsenate　[As(V)],　dimethylarsinic　acid　[DMA(V)]　and　two　arsenosugars,　was　investigated　by　mouse　experiments　in　this　study.　The　results　showed　that　the　intake　of　higher-dose　laver　did　not　lead　to　a　notable　increase　of　As(V)　concentration　in　mouse　muscle/organs　and　feces.　In　contrast,　DMA(V)　excretion　in　feces　and　DMA(V)　residue　in　muscle/organs　showed　a　close　correlation　with　laver-dose　intake.　Most　DMAsSugarMethoxy　was　translated　into　other　arsenic　species　and　then　was　together　excreted　out　via　mouse　feces;　two　dominant　arsenic　species,　arsenosugar　DMAsSugarMethoxy　and　DMAsSugarPhosphate,　were　not　detected　in　mouse　muscle/organs　after　20-Day　or　30-Day　feeding　whether　in　lower-dose　laver　groups　containing　1/36　(mass　ratio)　of　the　laver　in　mouse　feed　or　higher-dose　laver　groups　containing　1/6　(mass　ratio)　of　the　laver　in　mouse　feed.　About　65–77%　of　total　arsenic　digested　by　mouse　was　excreted　out　via　feces;　only　0.12–0.78%　of　it　was　accumulated　in　mouse　organs/muscle.　The　results　of　this　study　provided　valuable　knowledge　for　comprehending　the　stability　and　metabolic　characteristics　of　different　arsenic　species　from　Fujian　laver　in　vivo,　also　for　more　scientifically　assessing　the　intake　risk　of　arsenic　in　laver.　©　2021　Elsevier　B.V.